Pathology

Question 1

Infectious causes of granulomas

Answer 1

Mycobacteria, bartonella henselae (cat scratch), listeria (granulomatosis infantiseptica), tertiary syphillis, endemic fungi shistosoma

Question 2

Autoimmune granulomatous diseases

Answer 2

sarcoid, Crohn, PBC, subacute thyroiditis, Churgh-Strauss, GCA, Takyasu, Wegener

Question 3

Foreign material causing granulomas

Answer 3

Berylliosis, talcosis, hypersensitivity pneumonitis

Question 4

Cancer associated with hypercalcemia

Answer 4

Squamous cell carcinomas of various organs (PTHrP) and lymphoma (calcitrol)

Question 5

Cancer associated with Cushing and SIADH

Answer 5

small cell of the lung

Question 6

Cancer associated with pure red cell aplasia and Good syndrome (hypogammaglobulinemia)

Answer 6

thymoma

Question 7

Cancers assoc. w/ Trousseau and NBTE

Answer 7

adenocarcinomas, especially pancreatic

Question 8

Cancers assoc. w/ anti-NMDA receptor encephalitis

Answer 8

ovarian teratoma

Question 9

Cancers assoc. w/ opsoclonus-myoclonus ataxia syndrome (dancing hands, dancing feet)

Answer 9

neuroblastoma in kids, small cell lung cancer in adults

Question 10

Cancers assoc. w/ paraneoplastic cerebellar degeneration (antibodies vs. Hu, Yo, and Tr in Purkinje cells)

Answer 10

small cell lung cancer, gynecologic and breast, Hodgkin lymphoma

Question 11

cancers assoc. w/ paraneoplastic encephalomyelitis (antiboies vs. Hu in neurons)

Answer 11

small cell lung cancer

Question 12

Cancers assoc. w/ lambert-eaton

Answer 12

small cell lung cancer

Question 13

Cancer-causing HPV strains

Answer 13

16, 18

Question 14

Psammoma bodies seen in…

Answer 14

papillary carcinoma of thyroid, serous papilary cystadenocarcinoma of ovary, meningioma, malignant mesothelioma

Question 15

Breast cancer marker

Answer 15

CA 14-3/CA 27-29

Question 16

Pancreatic adenocarcinoma marker

Answer 16

CA 19-9

Question 17

Ovarian cancer serum marker

Answer 17

CA 125

Question 18

Cytokines that mediate cachexia

Answer 18

TNF-alpha, IFN-gamma, IL-1, IL-6

Question 19

Cancer assoc. w/ ALK onocogene

Answer 19

lung adenocarcinoma

Question 20

Cancer assoc. w/ BRAF oncogene

Answer 20

melanoma, NHL

Question 21

Cancer assoc. w/ KRAS oncogene

Answer 21

colon, lung, pancreatic

Question 22

Cancer assoc. w/ MYCL1 oncogene

Answer 22

lung tumor

Question 23

Cancer assoc. w/ MYCN oncogene

Answer 23

neuroblastoma

Question 24

cancer assoc. w/ RET oncogene

Answer 24

MEN 2a and 2b, medullary thyroid cancer

Question 25

cancer from loss of CDKN2A

Answer 25

melanoma, pancreatic cancer (p16, blocks G1 to S)

Question 26

cancer from loss of DCC

Answer 26

colon cancer (Deleted in Colon Cancer)

Question 27

cancer from loss of DPC4/SMAD4

Answer 27

pancreatic cancer (deleted in pancreatic cancer)

Question 28

Cancer assoc. w/ aflatoxin

Answer 28

HCC

Question 29

Cancer assoc. w/ aromatic amines

Answer 29

transitional cell carcinoma of bladder

Question 30

Cancers assoc. w/ arsenic

Answer 30

liver angiosarcoma, lung cancer, squamous cell carcinoma of skin

Question 31

Cancer assoc. w/ ionizing radiation

Answer 31

papillary thyroid carcinoma

Question 32

Cancer assoc. w/ radon

Answer 32

lung cancer

Question 33

cancer assoc. w/ vinyl chloride

Answer 33

liver angiosarcoma