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Flashcards in Pathology Deck (33):
1

Infectious causes of granulomas

Mycobacteria, bartonella henselae (cat scratch), listeria (granulomatosis infantiseptica), tertiary syphillis, endemic fungi shistosoma

2

Autoimmune granulomatous diseases

sarcoid, Crohn, PBC, subacute thyroiditis, Churgh-Strauss, GCA, Takyasu, Wegener

3

Foreign material causing granulomas

Berylliosis, talcosis, hypersensitivity pneumonitis

4

Cancer associated with hypercalcemia

Squamous cell carcinomas of various organs (PTHrP) and lymphoma (calcitrol)

5

Cancer associated with Cushing and SIADH

small cell of the lung

6

Cancer associated with pure red cell aplasia and Good syndrome (hypogammaglobulinemia)

thymoma

7

Cancers assoc. w/ Trousseau and NBTE

adenocarcinomas, especially pancreatic

8

Cancers assoc. w/ anti-NMDA receptor encephalitis

ovarian teratoma

9

Cancers assoc. w/ opsoclonus-myoclonus ataxia syndrome (dancing hands, dancing feet)

neuroblastoma in kids, small cell lung cancer in adults

10

Cancers assoc. w/ paraneoplastic cerebellar degeneration (antibodies vs. Hu, Yo, and Tr in Purkinje cells)

small cell lung cancer, gynecologic and breast, Hodgkin lymphoma

11

cancers assoc. w/ paraneoplastic encephalomyelitis (antiboies vs. Hu in neurons)

small cell lung cancer

12

Cancers assoc. w/ lambert-eaton

small cell lung cancer

13

Cancer-causing HPV strains

16, 18

14

Psammoma bodies seen in...

papillary carcinoma of thyroid, serous papilary cystadenocarcinoma of ovary, meningioma, malignant mesothelioma

15

Breast cancer marker

CA 14-3/CA 27-29

16

Pancreatic adenocarcinoma marker

CA 19-9

17

Ovarian cancer serum marker

CA 125

18

Cytokines that mediate cachexia

TNF-alpha, IFN-gamma, IL-1, IL-6

19

Cancer assoc. w/ ALK onocogene

lung adenocarcinoma

20

Cancer assoc. w/ BRAF oncogene

melanoma, NHL

21

Cancer assoc. w/ KRAS oncogene

colon, lung, pancreatic

22

Cancer assoc. w/ MYCL1 oncogene

lung tumor

23

Cancer assoc. w/ MYCN oncogene

neuroblastoma

24

cancer assoc. w/ RET oncogene

MEN 2a and 2b, medullary thyroid cancer

25

cancer from loss of CDKN2A

melanoma, pancreatic cancer (p16, blocks G1 to S)

26

cancer from loss of DCC

colon cancer (Deleted in Colon Cancer)

27

cancer from loss of DPC4/SMAD4

pancreatic cancer (deleted in pancreatic cancer)

28

Cancer assoc. w/ aflatoxin

HCC

29

Cancer assoc. w/ aromatic amines

transitional cell carcinoma of bladder

30

Cancers assoc. w/ arsenic

liver angiosarcoma, lung cancer, squamous cell carcinoma of skin

31

Cancer assoc. w/ ionizing radiation

papillary thyroid carcinoma

32

Cancer assoc. w/ radon

lung cancer

33

cancer assoc. w/ vinyl chloride

liver angiosarcoma