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Flashcards in Respiratory Deck (47):
1

Name the order of stages of respiratory development and the weeks

embryonic (4), pseudoglandular (5-16), canalicular (16-26), saccular (26-birth), alveolar (32-birth)

2

Malformations associated with Potter sequence

bilateral renal agenesis, pulmonary hypoplasia, diaphragmatic hernia

3

collapsing pressure =

2*tension/radius

4

goblet cells end at this level in lung

end of bronchi

5

cartilage ends at this level in lung

end of bronchi

6

smooth muscle ends at this level in lung

terminal bronchioles

7

pseudostratified epithelium ends at this level in lung

ends with terminal bronchioles

8

inspiratory capacity =

inspiratory reserve + tidal

9

functional residual capacity =

Expiratory Reserve + residual

10

vital capacity =

expiratory reserve + tidal + inspiratory reserve

11

physiologic dead space =

anatomic ds + alveolar ds
= Vt (PaCO2 - PeCO2) / PaCO2

where little a is arterial

12

Va (alveolar ventilation) =

(Vt-Vd)*RR

13

Oxygen content =

1.43Hb*SaO2 + 0.003*PaO2

14

Resistance (of fluid/air) =

8nl/pir4

15

Pa/A/v and V/Q in Zone 1

PA > Pa > Pv. V/Q = 3

16

Pa/A/V and V/Q in Zone 2

Pa > PA > Pv. V/Q = 1

17

Pa/A/v and V/Q in Zone 3

Pa > Pv > PA. V/Q = 0.6

18

Haldane effect

high O2 unloads CO2

19

Bohr effect

high CO2 unloads O2

20

Winter's formula is used for

acidosis only. pH = 1.5*bicarb + 8

21

anterior epistaxis from

Kiesselbach plexus

22

posterior epistaxis from

sphenopalatine artery, a branch of maxillary artery

23

Reid ratio is relevant in this disease

chronic bronchitis

24

ferruginous bodies in this pneumoconiosis

asbestosis

25

granulomas in this pneumoconiosis

berylliosis

26

eggshell calcification of hilar nodes in this pneumoconiosis

silicosis

27

tb susceptibility in this pneumoconiosis

silicosis

28

the only pneumoconiosis which affects lower lobes

asbestos

29

these are increased in the serum in those with sarcoid

ACE and Ca2+

30

drugs that cause ILD

bleomycin, busulfan, amiodarone, methotrexate

31

what is Caplan syndrome

rheumatoid arthritis and pneumoconiosis with intrapulmonary nodules

32

mutation in heritable PHTN

loss of function BMPR2

33

what is cyclothorax

pleural effusion due to lymphatic obstruction/injury

34

MCCs lobar pneumonia

s pneumo, legionella, klebsiella

35

MCCs bronchopneumonia

s pneumo, s aureus, h flu, klebsiella

36

MCCs interstitial pneumonia

mycoplasma, chlamydia, legionella, viruses

37

tx lung abscess with

clindamycin

usually due to anaerobes (bacteroides, fusobacterium, peptostreptococcus) or s aureus

38

mesothelioma histologic markers

cytokeratin, calretinin

39

stain for neuroendocrine cells

chromogranin A. small cell lung is also neuron-specific enolase-positive

40

paraneoplastic syndromes for small cell lung cancer

cushing, SIADH, Lambert-Eaton, antibodies vs. neurons

41

class of drugs: diphenhydramine, dimenhydrinate, chlorpheniramine

first generation H1 inhibitors

42

class of drugs: loratadine, fexofenadine, deslortadine, cetirizine

second generation H1

43

bosentan MOA

antagonizes endothelin 1. used for PHTN

44

long acting beta agonists for asthma

salmeterol, formeterol

45

MOA montelukast, zafirlukast

block leukotriene receptor CysLT1

46

MOA zileuton

block 5-lipoxygenase pathway to inhibit leukotriene synthesis

47

anti IgE antibody for asthma

omalizumab