Pharmacology Exam 1 Flashcards Preview

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Flashcards in Pharmacology Exam 1 Deck (117)
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1

Substances that produce responses within the body, they are synthesized by cells of the human body, animal cells, or microorganismsEx: Insulin

Biologics

2

Treatments that consider the health of the whole person and promote disease prevention, natural, not drugs or medicineEx: herbs, acupuncture, massage, meditation

Complementary and Alternative Medicines

3

Major differences between prescription and OTC drugs

Prescription: need written order from a doctorOTC: doesn't need a prescription, has lower dosage and safer

4

Role of the FDA in the drug approval process

Reviews drugs that have worked and gone through the New Drug Application (NDA) process. Once they approve it, the drug is put on the market

5

US agency responsible for the evaluation and approval of new drugs

FDA

6

Federal law enforcement agency that combats drug smuggling and monitors controlled substances

Drug Enforcement Administration (DEA)

7

4 phases of the drug approval process

1. preclinical investigation: drugs are tested on animals or human cells2. clinical investigation: tests on healthy human volunteers as well as people with a disease3. New Drug Application: completed if the drug appears to work and reviewed by the FDA4. Post marketing surveillance: drug is marketed but still monitored

8

Method for organizing drugs on the basis of their clinical usefulness, tells you exactly what the drug is going to do in the bodyEx: raises your BP

Therapeutic classification

9

Method for organizing drugs on the basis of their mechanism of action (at the molecular & body system levels)

Pharmacologic classification

10

Well understood model drug with which other drugs in a pharmacologic class may be compared

Prototype drug

11

Strict chemical nomenclature used for naming drugs established by the IUPAC, used in the lab

Chemical name

12

Nonproprietary name of a drug assigned by the government, stays the same throughout all companies

Generic name

13

Proprietary name of a drug assigned by the manufacturer, also called the brand or product name, usually easier to understand, most patients know this name

Trade name

14

Drug product with more than one active generic ingredient

Combination drug

15

The ability of a drug to reach the bloodstream and its target tissues

Bioavailability

16

The continued drive to use a substance despite its negative health and social consequences

Addiction

17

Strong physiological or psychological need for a substance.. associated with tolerance, you will keep needing more

Dependence

18

A drug placed into one of the five categories based on its potential for misuse or abuse

Scheduled drug

19

How a drug produces its physiological effect on the body

Drug's mechanism of action

20

Description and example of a SCHEDULE 1

No medical use, very high potential for abuseEx: heroine, LSD, marijuana

21

Description and example of a SCHEDULE 2

High potential for abuseEx: morphine, methadone

22

Description and example of a SCHEDULE 3

Potential for abuse, but less than schedule 1 and 2Ex: codeine

23

Description and example of a SCHEDULE 4

May cause dependenceEx: benzodiazepine

24

Description and example of a SCHEDULE 5

Very limited potential for dependenceEx: codeine

25

The process of moving a drug across the body's membranes from the spot of administration

Absorption

26

The process of transporting drugs through the body, tissues, heart, kidneys, brain, usually through the blood stream

Distribution

27

The total of all biochemical reactions in the body, or biotransformation

Metabolism

28

The process of removing drugs or substances from the bodyEx: by the kidneys through the urine

Excretion

29

What are the 4 phases of pharmacokinetics

AbsorptionDistributionMetabolismExcretion

30

The study of how drugs are handled in the body

Pharmacokinetics