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Flashcards in pulmpath2 Deck (7)
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1

What do obstructive diseases limit?

limitation of airflow
increase in resistance due to partial or complete obstruction
-have trouble letting the air out

2

What does a restrictive disease reduce?

reduces expansion of lung parenchyma

3

What are examples of obstructive airway diseases, how is the FEV1 affected?

Decreased FEV1
-increase in resistance to airflow due to obstruction at any level

EX:
1. emphysema
2. chronic bronchitis
3. bronchiectasis
4. asthma
5. tumor
6. foreign body

4

What are examples of obstructive airway diseases, how is the FEV1 and TLC affected?

Normal FEV1, Decreased TLC
-reduced expansion of lung parenchyma with decrease in total lung capacity

EX:
Chest wall disorders (polio, obesity, pleural disease, kyphoscoliosis)
Interstitial/ Infiltrative diseases (ARDS, dust disease, interstitial fibrosis)

5

What does a pulmonary function curve look like in obstructive vs. restrictive lung disease?

Obstructive-shift in curve but size remains the same
Restrictive-same shape but smaller

6

What are 4 key obstructive pulmonary diseases?

1. Asthma
2. chronic bronchitis
3. emphysema
4. bronchiectasis

7

What is asthma?

intermittent and reversible airway obstruction
-increased responsiveness of the tracheobronchial tree to various stimuli
-multiple genes+environment
-chronic bronchial inflammation with eosinophils
-bronchial smooth muscle hypertrophy hyperreactivity
-increased mucus production

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