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Flashcards in Respiratory diseases of pigs Deck (85)
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31

Should you use culture to diagnose mycoplasma hyopneumoniae?

NO!

32

What is the epidemiology of mycoplasma hyopneumoniae?

1. two to three weeks
2. horizontal transmission (sow-piglet, pig-pig)
3. expression in GROWER PIGS >10WEEKS
4. regional spread via aerosol

33

Is the epizootic herd presentation of mycoplasma hypneumoniae common or uncommon?

uncommon

34

What are the issues with using serology to diagnose mycoplasma hyopneumoniae at the herd level?

No correlation between vaccine titre and protection
seroconversion HIGHLY VARIABLE and may require 6wks in natural infection
LOW SENSITIVITY--not for individual pig (but specificity high)

35

Does toxogenic pasteurella multocida spread regionally?

no

36

What is the endemic herd presentation of mycoplasma hyopneumoniae?

1. chronically infected herds
2. exposed in GROWER BARN
3. coughing in early grower period
4. high morbidity, low mortality

37

What is the treatment and control for mycoplasma hyopneumoniae?

1. vaccination of sow, nursery, grower
2. strategic medication
3. environmental control
4. control other resp pathogens and ascarids (PRDC)

38

What are the clinical signs of Mycoplasma hyopneumoniae?

1. non-productive, dry raspy cough (uncomplicated)
2. productive coughing if concurrent infections
3. tacypnea, dyspnea
4. uneven growth rates

39

What is severity of enzootic penumoniae influenced by?

1. MH strain
2. pig flow
3. animals per air space
4. pen density
5. air quality

40

What environmental control can be done to prevent m. hyo pneumoniae infection?

improve indoor air quality
segregate age groups

41

How is mycoplasma hyopneumoniae diagnosed on an individual basis?

FAT-antigen
PCR-DNA

42

How is mycoplasma hyopneumoniae diagnosed on a population basis?

1. Serology
2. slaughter check scoring
3. confirmatory testing (PCR, FAT on slaughter lungs)

43

What are the issues with using serology to diagnose mycoplasma hyopneumoniae at the herd level?

No correlation between vaccine titre and protection
seroconversion HIGHLY VARIABLE and may require 6wks in natural infection
LOW SENSITIVITY--not for individual pig (but specificity high)

44

What are lungs score intervention levels for mycoplasma hyopneumoniae

individual lesions scores >5%
prevalence of infected lung >15-20%

45

Why might confirmatory testing of lungs at slaughter for myccoplasma hyopneumoniae be unreliable?

1. comingling of positive and negative pigs at assembly yard
2. scalding tank

46

What is the treatment and control for mycoplasma hyopneumoniae?

1. vaccination of sow, nursery, grower
2. strategic medication
3. environmental control
4. control other resp pathogens and ascarids (PRDC)

47

What are different vaccination strategies that can be used to control mycoplasma hyopneumoniae?

1. vaccinate sows, then delay piglet vaccination until maternal antibodies dropped
2. vaccinate progeny (suckling or nursery)

48

Does antimicrobial medication eliminate m. hyo infection?

NO. reduce infection pressure and control bacteiral infections

49

What environmental control can be done to prevent m. hyo pneumoniae infection?

improve indoor air quality
segregate age groups

50

What are three diseases that cause coughing and dyspnea?

1. mycoplasma hyopneumonia (enzootic pneumonia)
2. swine influenza virus
3. actinobacillus pleuropneumoniae

51

What type of virus is the swine influenza virus?

type A influenza virus (orthomyxoviridae)

52

What are the two ways swine influenza can evolve?

drift--point mutations
shift--reassortment

53

What was the original source of swine influenza virus?

humans

54

What type of swine influenza was seen from 1930-1998?

classic swine H1N1

55

What type of swine influenza emerged in 1998?

H3N2

56

How did the H3N2 virus originate?

from triple reassortment from human, swine and avian

57

What is the epidemiology of swine influenza?

1. highly infectious
2. most often late fall and winter
3. direct contact (nasopharyngeal secretions)
4. airborne spread in hog dense regions

58

What is the pathogenesis of swine influenza?

1. short incubation 1-3d
2. rapid replication
3. tropism for bronchiolar epithelium
4. cytokine secretion
5. epithelial cell necrosis
6. exudate accumulation
7. rapid virus clearance

59

What are the signs of classic H1N1?

1. explosive coughing (sudden onset)
2. paroxysms "seal bark"
3. high morbidity, low mortality
4. rapid recovery 5-7d

60

What are the clinical signs of modern swine fever?

1. variable and potentially subtle resp signs
2. all ages
3. herd presentation varies