S1L1: The Skin

Question 1

Largest organ in the human body

Answer 1

SKIN

Question 2

The skin is __% of total body weight

Answer 2

15%

Question 3

It is the external covering of the Body

Answer 3

Skin

Question 4

3 layers of skin

Answer 4

○ Epidermis
○ Dermis
○ Subcutaneous tissue/Hypodermis

Question 5

Function of the skin: Protection
[] suppresses bacterial growth (4 - 6.5 PH)

Answer 5

Acid mantle

Question 6

Function of the skin: Protection

Anti-microbial peptides or proteins that exert
an immunomodulatory & chemotactic function

Answer 6

Defensins

Question 7

Functions of the skin: Protection

■ Helps with healing of wound or burns
■ Evaporation of fluids from within
■ Helps with water retention & keeping the homeostasis of fluids in our body

Answer 7

Moisture barrier/water retention

Question 8

Functions of the skin: Immunity

First line of defense when there is a wound

Answer 8

Cells of Langerhans

Question 9

Functions of the skin: Immunity

Population of tissue resident macrophages
(WBC) that form a network of cells across the
epidermis.

Answer 9

Cells of Langerhans

Question 10

Functions of the skin: Immunity

These determine the appropriate adaptive
immune response or by interpreting the microenvironmental context in which they
encounter foreign substances

Answer 10

Cells of Langerhans

Question 11

Functions of the Skin: Immunity

Macrophages are type of [] blood cells

Answer 11

White Blood cells

Question 12

Functions of the Skin: Immunity

Keratinin cells produce ____. It is considered as a part of cytokines that have a central role in the regulation of immune & inflammatory responses or d/t sterile insult

Answer 12

interleukin 1 (inflammatory mediator)

Question 13

Functions of the skin: Immunity

Aids in the inflammatory process when there
is a wound in the area.

Answer 13

Keratinin cells

Question 14

Functions of the skin: Thermoregulation

___ to cool down and ___ to conserve heat

Answer 14

vasodilation to cool down and vasoconstrict to conserve heat

Question 15

Functions of the skin: Thermoregulation

Excretion of ___ cools the body

Answer 15

Sweat

Question 16

Functions of the skin: Storage & Synthesis

Excretions/absorption/synthesis of [] for development of bones

Answer 16

Vitamin D

Question 17

Function of the skin: Storage & Synthesis

The skin stores the following (3)

Answer 17

1. Vitamin D
2. Lipids and water
3. Blood reservoir - Presence of numerous vessels allow the thermoregulation of the skin

Question 18

Enumerate the functions of the skin (6)

Answer 18

1. Protection
2. Immunity
3. Thermoregulation
4. Sensation
5. Sweat production
6. Storage & Synthesis