Test 1 chapter 8 Flashcards Preview

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Flashcards in Test 1 chapter 8 Deck (33)
1

rapid
nonspecific
short-lived

inflammatory response

2

slower
specific
long-lived memory

adaptive immune response

3

substances capable pf generating an immune response
"non self"

antigens

4

associated with the body fluids and due to the production of soluble proteins call antibodies

humoral immunity

5

associated with the development of "trained" armies of the T lymphocytes

cellular immunity

6

antibodies circulate in the blood and binds to antigens on infectious agents. this can result in direct or indirect response

humoral immunity

7

inactivates microorganism

direct response

8

activates inflammatory mediators that destroy pathogen

indirect

9

antibodies are responsible for protection against what

many bacteria and viruses

10

T cell differentiation which lead to direct, indirect or avoid attacking self

cellular immunity

11

cell mediated immunity protects against what

viruses and cancer

12

lymphocytes that downgrade the immune response and also provide tolerance to self

T regulatory cells

13

lymphocytes that are trained killer cells, they destroy host cells infected by bacteria/viruses and cancer cells

Cytotoxic T cells

14

have perviously encountered and responded to their antigen

memory T cells

15

react with antibodies/antigen receptors on B and T cells to induce immune response

antigens

16

Immunogenicity

Foreignness
Molecular size
chemical complexity
sufficient quantity

17

Most abundant antibody
Can cross capillary walls to enter or exit tissue
Can cross the placenta giving the newborn immediate protection to all the disease and vaccinations the moth has ever had

IgG

18

made after IgM and IgG against same antigen
found in mucus membranes

IgA

19

largest and most effective antibody
made first in response to infection
blood types

IgM

20

mediates parasitic and allergic response

IgE

21

located on the surface of B lymphocyte memory cells

IgD

22

antigens require processing and presentation by what

antigen presenting cells APC

23

APC activates what

T helper cells

24

For processing and presentation...

Antigen must be appropriate type
Lymphocytes must be prepared to recognize presented antigen
Antigen must be presented appropriately

25

help antigen-driven maturation of B and T cells
Facilitate and magnify interaction between APCs and immunocompetent lymphocytes

Helper T cells

26

step of helper T cells

TH interacts through antigen-specific and antigen independent mechanisms
Undergoes differentiation
Mature Th interacts with plasma or T effector cells

27

provide help in developing cell-immdiated immunity

TH1 cell subsets

28

provide help in developing humoral immunity

TH2 cell substrates

29

Latent period after novel antigen exposure
After 5-7 days IgM antibody detected
IgG response but more IgM

primary response

30

more rapid with larger antibody amounts
Presence of memory cells, differentiation not required
IgG produced in greater amounts

secondary response

31

adaptive immunity can be either

passive or active

32

antibodies or T cells produced after either natural exposure to antigen or immunization
Long-lived

Active immunity

33

Preformed antibodies or T lymphocytes are transferred from donor to recipient Ex. placenta
Short-lived

passive immunity