Test 3 Endocrine Flashcards Preview

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Flashcards in Test 3 Endocrine Deck (31)
1

Function of endocrine glands

synthesize, store, and release hormones into blood

2

Hormones of the Hypothalamus gland and their target cells

Thyrotropin-releasing TRH
Corticotropin-releasing CRH
Anterior pituitary

3

Hormones of the anterior pituitary gland and their target cells

Adrenocorticotropic ACTH Adrenal cortex
Thyroid-stimulating TSH thyroid

4

Hormones of the posterior pituitary and their target cells

Antidiuretic(vasopressin) ADH
kidney

5

Hormones of the thyroid gland and their target cells

Thyroxine T4
triiodothyronie T3
systemic cells

6

Hormones of the adrenal cortex and their target cells

mineralcorticosteroids (aldosterone) kidneys
Glucocorticoids (cortisol) most tissues

7

Hormones of the pancreas and their target cells

insulin
muscles, tissues

8

problems that occur when their is lack of negative feedback inhibition

excessive hormone production
Failure of "turn off" system

9

Gland destruction (infection, tumor compression, autoimmune attack)
Hormone production genetic defect (gene deletion/mutation, enzymatic deficit)
EX: DM, congenital adrenal hyperplasia

Hormone deficiency

10

Gland overproduction, nonendocrine tissue or tumore production
EX: cushings syndrome, anabolic steroid abuse, Graves disease

hormone excess

11

Aberrant increase in hormone level which causes a decrease in available receptors
EX: DM, type 2

hormone resistance

12

ADH insufficiency

Diabetes insipidus

13

3 types of diabetes insipidus

Neurogenic
Nephrogenic
Dipsogenic

14

Insufficient amounts of ADH
Lesion of hypothalamus, pituitary stalk, posterior pituitary

Neurogenic

15

Inadequate response to ADH
Genetic or acquired

nephrogenic

16

decrease in plasma osmolarity- below threshold
Excessive fluid intake

Dipsogenic

17

RX for neurogenic DI

ADH replacement (synthetic vasopressin)

18

RX for nephrogenic DI

reverse underlying disorder
Replace electrolytes
Thiazide in moderation

19

Lab tests for DI

urine specific gravity 300

20

Excess ADH secretion which leads to H2O intoxication and hyponatremia

Syndrome of inappropriate antidiuretic hormone SIADH

21

Lab test for SIADH

serum Na

22

inadequate production of TH or hormone resistance

hypothyroidism

23

Lack of TH negative feedback on pituitary TSH secretion and hypothalamic TRH secretion
LOw levels of TH and high elves of TSH and TRH

primary thyroid malfunction

24

Lack of negative feedback to hypothalamic release of TRH by TSH and thyroid TH
Low levels of TSH and TH and high levels of TRH

pituitary malfunction

25

Decreased TRH
Low levels of TRH, TSH, and TH

hypothalamic malfunction

26

is a diminished level of consciousness associated with sever hypothyroidism

myxedema coma

27

Thyroid gland over activity
Too much T4

hyperthyroidism

28

increased TH decreased TSH
primary or secondary hyperthyroidism?

Primary

29

Increased TH and TSH
primary or secondary hyperthyroidism

secondary

30

Decreased cortisol
Caused by autoimmune adrenal cortex distraction or Acute steroid withdrawal

Addison Disease

31

Clinical manifestations of addison disease

Addisonian crisis
Pigmentation
decreased serum Na
increased serum K