Test 1 chapter 9 Flashcards Preview

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Flashcards in Test 1 chapter 9 Deck (14)
1

exaggerated immune response against environmental antigens
Ex hey fever

allergy

2

immune response against beneficial foreign tissue
Ex. transfusion, transplant rejection

alloimmunity

3

immune response directed against "self"
Ex. systemic lupus erythematosis

autoimmunity

4

response insufficient to protect host
Ex. AIDS

immune deficiency

5

altered immunologic response to antigen which causes damage to host

hypersensitivity

6

reactions that occur within minutes to a few hours are

immediate hypersensitivity reactions

7

may take several hours to appear and are at maximum severity days after reexposure to the antigen

delayed hypersensitivity reactions

8

most rapid and sever hypersensitivity response
Immediate

anaphylaxis

9

reaction that are mediated by antigen specific IgE and the products of tissue mast cells
Occur against environmental antigens and are therefor allergic

Hypersensitivity type 1

10

side effects of type 1 hypersensitivity

itching
urticaria
conjunctivitis
rhinitits
GI cramps or malabsorption
decrease in BP
bronchospasm

11

Tissue-specific
IgG or IgM binds to specific tissue antigen on cell surface and activates complement cascade which causes membrane damage and lysis
Manifestations are tissue dependent

Type II hypersensitivity

12

antigen-antibody complexes formed in blood and deposited in vessel wall or extravascular tissue

Type III hypersensitivity

13

mediated by T lymphocytes not antibodies

type IV hypersensitivity

14

Type IV occurs through either

cytotoxic t lymphocytes or TH1 cells