(10) Sedative to Antipsychotics SLO Flashcards Preview

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Flashcards in (10) Sedative to Antipsychotics SLO Deck (66):
1

ALL sedative hypnotics cause __?__, some more so than others. Think alcohol intoxication.
A. Renal failure
B. Steven Johnson‘s Syndrome
C. Bad breath
D. Blindness
E. Drug-induced amnestic state

Drug-induced amnestic state

2

Antidepressants and anti epileptic drugs (AEDs) are associated with an increased risk of __?__.
A. Suicide
B. Early onset Parkinson’s disease
C. EPS
D. Antimuscarinic symptoms
E. Stroke

Suicide

3

Antipsychotics are associated with an increased risk of __?__.
A. Alopecia
B. A withdrawal syndrome in neonates
C. Weight loss
D. Enhanced alertness
E. Bone cancer

Withdrawal syndrome in neonates

4

Benzodiazepines, non-benzodiazepine sedative hypnotics and barbiturates all cause __?__.
A. Tolerance
B. Dependence
C. Withdrawal Syndrome
D. Some degree of amnesia
E. All the above

All of the above

5

Benzodiazepines, non-benzodiazepine sedative hypnotics and barbiturates all have __?__.
A. Antimuscarinic symptoms
B. A risk of EPS
C. Control schedule I listing
D. A Withdrawal syndrome.
E. A Narrow therapeutic margin

A withdrawal syndrome

6

Beta blockers have __?__.
A. A Narrow therapeutic margin
B. A Withdrawal syndrome
C. A risk of EPS
D. Antimuscarinic symptoms
E. Control schedule I listing

A withdrawal syndrome

7

Don’t take zolpidem __?__
A. With water
B. At bedtime
C. With food or immediately after a meal
D. None of the answers listed is correct.
E. After bathing

With food or immediately after a meal

8

Elderly patients with dementia-related psychosis are more likely to __?__ when given antipsychotics - hence the boxed warning on all antipsychotics.
A. Have kidney problems
B. Have liver problems
C. Have cardiovascular problems
D. Die
E. Improve

Die

9

Having the HLA-B 1502 allele (a variant of the HLA-B gene) predisposes patients on carbamazepine to __?__
A. Blood dyscrasias
B. Steven Johnson’s Syndrome
C. Epilepsy
D. Heart disease
E. Psychosis

Steven Johnson's Syndrome

10

Lithium causes goiter because it __?__.
A. Has antimuscarinic symptoms
B. Has a Narrow therapeutic margin
C. Causes weight gain
D. Has a Withdrawal syndrome.
E. Inhibits the release of thyroid hormone

Inhibits the release of thyroid hormone

11

Lithium causes __?__.
A. Tremor
B. Hair loss
C. Weight gain
D. Memory loss
E. All the above

All the above

12

Lithium has __?__.
A. None of the listed answers is correct.
B. Anticholinergic effects
C. A lifetime maximum dose
D. A Narrow therapeutic margin
E. A Control Schedule 1 listing

A Narrow therapeutic margin

13

MAOIs are associated with __?__.
A. Neuroleptic malignant syndrome
B. Tolerance
C. Malignant hyperthermia
D. Serotonin syndrome
E. Dependence

Serotonin Syndrome

14

Phenobarbital has a long t ½ and is often associated with __?__.
A. Insomnia
B. Angina
C. Seizures
D. Hang-over
E. Arrhythmias

Hang-over

15

Phenobarbital is a potent __?__
A. P450 inducer
B. Benzodiazepine
C. TCA
D. SNRI
E. SSRI

P450 inducer

16

SSRIs have __?__.
A. A Withdrawal syndrome.
B. A risk of EPS
C. A Narrow therapeutic margin
D. Control schedule I listing
E. Analgesic effects

A withdrawal syndrome

17

TCAs are contraindicated with __?__ because the combination may cause hyperpyretic crises, convulsions and fatalities.
A. MAOIs
B. Non-BZD hypnotics
C. BZDs
D. Antihistamines
E. Barbiturates

MAOIs

18

The most commonly prescribed antidepressants, including SNRIs and SSRIs, are associated with __?__
A. Weight gain
B. Delayed onset (oftentimes weeks)
C. All the above
D. Sexual dysfunction
E. Potential effects on clotting

All the above

19

The onset of action for Eszopiclone is so rapid, it must be taken immediately before __?__.
A. Bathing
B. Drinking water
C. Going to bed
D. Eating
E. Getting up in the morning

Going to bed

20

Typical antipsychotics are associated with a greater risk of __?__ than atypicals.
A. Sedation
B. Anticholinergic effects
C. EPS
D. Sympathetic effects
E. All the above

All the above

21

When neonates have been exposed to antipsychotics during the 3rd trimerster of pregnancy, they are at increased risk of __?__.
A. Goiter
B. Hair loss
C. Weight gain
D. A Withdrawal syndrome.
E. Cataracts

A withdrawal syndrome

22

Which of the following is a 1st generation antihistamine used as a sedative, hypnotic, and to treat all allergic reactions and motion sickness as well as Parkinson’s movement disorders and EPS.
A. Divalproex
B. Diphenhydramine
C. Lamotrigine
D. Lithium
E. Carbamazepine

Diphenhydramine

23

Which of the following is a 1st generation antihistamine with anti cholinergic effects indicated to treat all allergic reactions, as a sedative/hypnotic and to treat PD/EPS?
A. Buspirone
B. Artane
C. Benztropine
D. Bupropion
E. Benadryl

Benadryl

24

Which of the following is Desyrel, a 5HT antagonist and Reuptake Inhibitor (SARI) used PO to treat MDD?
A. Benztropine
B. Bupropion
C. Trazodone
D. Buspirone
E. Selegiline

Trazadone

25

Which of the following is a 5HT1a agonist and a D2 antagonist, non-sedating anxiolytic?
A. Buspirone
B. Zolpidem
C. Eszopiclone
D. Phenobarbital
E. Propranolol

Buspirone

26

Which of the following is a Beta blocker and non-sedating anxiolytic indicated for HT, angina, performance anxiety, migraine, etc.
A. Propranolol
B. Carbamazepine
C. Lamotrigine
D. Lithium
E. Doxepin

Propranolol

27

Which of the following is a Butyrophenone (typical) antipsychotic given PO and IM to treat schizophrenia and Tourette’s disorder. It may be used off label as an antiemetic.
A. Clozapine
B. Olanzapine
C. Quetiapine
D. Chlorpromazine
E. Haloperidol

Haloperidol

28

Which of the following is a C-III barbiturate sedative hypnotic?
A. Thiopental (Pentothal)
B. Phenobarbital
C. Eszopiclone
D. Diphenhydramine
E. Buspirone

Thiopental (Pentothal)

29

Which of the following is a C-IV barbiturate sedative, hypnotic, AED?
A. Phenobarbital
B. Diphenhydramine
C. Zolpidem
D. Buspirone
E. Propranolol

Phenobarbital

30

Which of the following is a C-IV benzodiazepine (BZD) anxiolytic that is short-acting with active metabolites? Available PO only. T ½ varies from 6-24 hours, averaging about 12 hours.
A. Alprazolam
B. Midazolam
C. Carbamazepine
D. Diazepam
E. Lorazepam

Alprazolam

31

Which of the following is a C-IV BZD long-acting with active metabolites with many indications including acute alcohol withdrawal, epilepsy, tremors, athetosis, sedative/hypnotic, and it is used as an anxiolytic. Available PO, PR, IV, IM and the t ½ ranges from 24-60 hours and up to 10 days!
A. Alprazolam
B. Lorazepam
C. Carbamazepine
D. Diazepam
E. Midazolam

Diazepam

32

Which of the following is a C-IV BZD, it is short-acting with sedative, anxiolytic, amnesiac preanesthetic and status epilepticus control indications.
A. Phenobarbital
B. Carbamazepine
C. Lorazepam
D. Diazepam
E. Alprazolam

Lorazepam

33

Which of the following is a C-IV BZD? It is very short-acting without important active metabolites. Indications include sedation, anxiolysis and amnesia preanesthesia and induction of anesthesia. Available PO, IM, and IV with a t ½ of about 2.5 hours.
A. Alprazolam
B. Carbamazepine
C. Lorazepam
D. Diazepam
E. Midazolam

Midazolam

34

Which of the following is a C-IV non-BZD sedative hypnotic indicated for short-term use to treat insomnia. Available PO only with a t ½ of 2-2.5 hours.
A. Propranolol
B. Diazepam
C. Phenobarbital
D. Buspirone
E. Zolpidem

Zolpidem

35

Which of the following is a C-IV non-BZD sedative hypnotic indicated for short-term use to treat insomnia. It has such a rapid onset of action, it must be taken immediately before bed, preferably on an empty stomach.
A. Phenobarbital
B. Eszopiclone
C. Propranolol
D. Diphenhydramine
E. Buspirone

Eszopiclone

36

Which of the following is a Mood stabilizer for bipolar disorder (antimanic). VERY NARROW THERAPEUTIC MARGIN – therapeutic doses may be toxic.
A. Lamotrigine
B. Propranolol
C. Carbamazepine
D. Lithium
E. Doxepin

Lithium

37

Which of the following is a Phenothiazine (typical) antipsychotic given PO, IV or IM. Indications and uses include schizophrenia, nausea and vomiting control, anxiety, acute intermittent porphyria, adjunct to tetanus therapy, control of the manic phase of bipolar disorder, hiccups, severe behavior problems in kids marked by explosive and/or hyperactive behaviors and for the short-term treatment of ADHD kids with aggression, mood lability, etc.
A. Doxepin
B. Chlorpromazine
C. Risperidone
D. Carbamazepine
E. Clozapine

Chlorpromazine

38

Which of the following is a PO antiviral indicated to treat PD and Influenza A?
A. Ambien
B. Amantadine
C. Ativan
D. Artane
E. Alprazolam

Amantadine

39

Which of the following is a synthetic antispasmodic indicated to treat PD and EPS. Given PO only.
A. Ativan
B. Artane
C. Alprazolam
D. Amantadine
E. Ambien

Artane

40

Which of the following is a TCA given PO for MDD?
A. Remeron
B. Paxil
C. Zoloft
D. Pamelor
E. Cymbalta

Pamelor

41

Which of the following is a TeCA given PO for MDD? It is used off label as an antiemetic much like Ondansetron.
A. Trazodone
B. Mirtazapine
C. Bupropion
D. Duloxetine
E. Selegiline

Mirtazapine

42

Which of the following is a trade name for Bupropion?
A. Alplenzin
B. Wellbutrin
C. Zyban
D. Chantix
E. A, B and C, not D

A, B and C, not D

43

Which of the following is an AED indicated for epilepsy and bipolar disorder? PO only.
A. Amitriptyline
B. Diazepam
C. Lamotrigine
D. Duloxetine
E. Phenobarbital

Lamotrigine

44

Which of the following is an AED indicated for epilepsy, migraine and mania? PO only. Other salts include valproic acid and valproate.
A. Diazepam
B. Duloxetine
C. Divalproex
D. Diphenhydramine
E. Doxepin

Divalproex

45

Which of the following is an AED indicated for epilepsy, trigeminal neuralgia, acute manic & mixed episodes of bipolar disorder. Available PO only.
A. Lorazepam
B. Carbamazepine
C. Midazolam
D. Diazepam
E. Alprazolam

Carbamazepine

46

Which of the following is an Anti-cholinergic (combination of atropine and diphenhydramine) indicated to treat PD and EPS? Available PO, IV and IM.
A. Bupropion
B. Benztropine
C. Benadryl
D. Artane
E. Buspirone

Benztropine

47

Which of the following is an Atypical antipsychotic given IM or PO to treat schizophrenia and bipolar disorder? It is used off label as an antiemetic much as Ondansetron would be used.
A. Olanzapine
B. Clozapine
C. Haloperidol
D. Risperidone
E. Quetiapine

Olanzapine

48

Which of the following is an Atypical antipsychotic given PO (only) for treatment resistant schizophrenia and to decrease the risk of suicide?
A. Chlorpromazine
B. Quetiapine
C. Clozapine
D. Haloperidol
E. Carbamazepine

Clozapine

49

Which of the following is an Atypical antipsychotic given PO to treat schizophrenia and bipolar disorder as well as irritability associated with autism? This atypical has a high risk of EPS compared to other atypicals and is associated with a withdrawal syndrome in neonates.
A. Quetiapine
B. Risperidone
C. Clozapine
D. Haloperidol
E. Olanzapine

Risperidone

50

Which of the following is an MAOI available in PO and TD formulations to treat PD and MDD?
A. Emsam
B. Eldepryl
C. Selegiline
D. All the above
E. None of the above

All the above

51

Which of the following is an SNRI given PO and indicated to treat MDD, anxiety, fibromyalgia, and diabetic neuropathic pain?
A. Sertraline
B. Trazodone
C. Mirtazapine
D. Duloxetine
E. Selegiline

Duloxetine

52

Which of the following is an SNRI given PO and indicated to treat MDD.
A. Paroxetine
B. Trihexyphenidyl
C. Haloperidol
D. Chlorpromazine
E. Venlafaxine

Venlafaxine

53

Which of the following is the L isomer of citalopram (the biologically active form), an SSRI given PO for anxiety and MDD?
A. Valium
B. Lexapro
C. Buspar
D. Ambien
E. Celexa

Lexapro

54

Which of the following is the SSRI “Celexa” given PO for MDD?
A. Fluoxetine
B. Sertraline
C. Escitalopram
D. Citalopram
E. Paroxetine

Catalopram

55

Which of the following is the SSRI “Paxil” given PO for MDD and anxiety?
A. Citalopram
B. Fluoxetine
C. Sertraline
D. Paroxetine
E. Escitalopram

Paroxetine

56

Which of the following is the SSRI “Prozac” given PO for MDD, anxiety, and premenstrual dysphoric disorder?
A. Paroxetine
B. Escitalopram
C. Fluoxetine
D. Sertraline
E. Citalopram

Fluoxetine

57

Which of the following is the SSRI ”Zoloft” given PO for MDD, panic disorder, OCD?
A. Sertraline
B. Escitalopram
C. Fluoxetine
D. Paroxetine
E. Citalopram

Sertraline

58

Which of the following is the TCA “Sinequan” given PO for MDD, anxiety, alcoholism or bipolar disorder?
A. Duloxetine
B. Divalproex
C. Diazepam
D. Doxepin
E. Diphenhydramine

Doxepin

59

Which of the following is the TCA “Tofranil” given PO for MDD and childhood enuresis?
A. Fluoxetine
B. Mirtazapine
C. Nortriptyline
D. Imipramine
E. Citalopram

Imipramine

60

Which of the following is the Typical antipsychotic Navane given PO or IM to control schizophrenic behavior? It sometimes turns the urine pink.
A. Thiopental
B. Topamax
C. Tegretol
D. Thiothixene
E. Thorazine

Thiothixene

61

Which of the following is “Seroquel,” an Atypical antipsychotic given PO to treat schizophrenia, MDD and bipolar disorder? Patients must be monitored for cataract development, a risk with this drug.
A. Risperidone
B. Clozapine
C. Quetiapine
D. Olanzapine
E. Haloperidol

Queiapine

62

Which of the following was originally added to patent medicines in the 1800's to treat gout? Even 7-UP originally contained some of this "happy" making mineral.
A. Carbamazepine
B. Doxepin
C. Propranolol
D. Lamotrigine
E. Lithium

Lithium

63

Which of these is an “Other” antidepressant used PO to treat MDD and SAD. The trade names have different indications and one is only used for smoking cessation.
A. Selegiline
B. Alprazolam
C. Trazodone
D. Bupropion
E. Buspirone

Bupropion

64

While all of the benzodiazepines are on the Beer's List, __?__ is a BZD that is replacing diazepam to sedate elderly people due to the fact that it has no active metabolites and it is short acting.
A. Lorazepam
B. Haloperidol
C. Zolpidem
D. Olanzapine
E. Citalopram

Lorazepam

65

Women and the Elderly/debilitated patients/hepatic impaired, should be given __?__ the normal zolpidem or eszopiclone dose.
A. Twice
B. ¼
C. Triple
D. More than
E. Half

Half

66

Which of the following is the TCA “Elavil” given PO for MDD?
A. Duloxetine
B. Clozapine
C. Selegiline
D. Alprazolam
E. Amitriptyline

Amitriptyline