(6)Autocoid SLO Flashcards Preview

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Flashcards in (6)Autocoid SLO Deck (28):
1

1st generation antihistamines, like diphenhydramine, are associated with __?__.
A. Dry eyes, mouth, throat and an inability to sweat (easily over heated)
B. Urinary retention
C. Sedation
D. Antimuscarinic effects
E. All of the above

Dry eyes, mouth, throat and an inability to sweat (easily over heated), urinary retention, sedation, antimuscarinic effects - ALL

2

A drug name ends in “pril,” what is the drug class?
A. LOX inhibitor
B. ACEI
C. LT Receptor blocker
D. NSAID
E. ARB

ACEI

3

A drug name ends in “sartan,” what is the drug class?
A. NSAID
B. ACEI
C. Anticholinergic
D. ARB
E. LOX inhibitor

ARB

4

A meal high in fat can substantially reduce the absorption of __?__.
A. Ibuprofen
B. Diphenhydramine
C. Promethazine
D. Benazepril
E. Aliskiren

Aliskiren (Tekturna)

5

ACEI are associated with __?__.
A. Ibuprofen
B. Diphenhydramine
C. Promethazine
D. Benazepril
E. Aliskiren

Angioedema, fetotoxicity in the 2nd and 3rd trimester, acute renal failure, potassium retention (Hyperkalemia) - ALL

6

ARBs are associated with __?__.
A. Sedation
B. Fetotoxicity in the 2nd and 3rd trimester
C. Diarrhea, nausea
D. Hyperkalemia
E. B, C and D only

Fetotoxicity in the 2nd and 3rd trimester, Diarrhea, nausea, Hyperkalemia **NOT SEDATION**

7

Corticosteroids are associated with __?__.
A. Gastric ulcers
B. Sedation
C. Antimuscarinic effects
D. Angioedema
E. Cataracts

Cataracts

8

H2 ANTagonists are known as __?__
A. Gastric acid reducers
B. Antidepressants
C. Antihistamines
D. Antihypertensives
E. Anti Migraine

Gastric acid reducers

9

Loratadine has a long half-life, therefore it is administered less frequently than 1st generation antihistamines like __?__
A. Buspirone
B. Valsartan
C. Fluoxetine
D. Azelastine
E. Diphenhydramine

Diphenhydramine (Benadryl)

10

Misoprostol will cause __?__
A. Abortion in pregnant woman
B. Severe tissue injury regardless of administration route
C. Fatal respiratory depression in kids
D. Suicide
E. 1st dose anaphylaxis

Abortion in pregnant women

11

NSAIDs are associated with __?__
A. Dry mouth, dry eyes
B. Gastric ulcers
C. Myalgia
D. Sedation
E. Cataracts

Gastric Ulcers

12

Patients already on a diuretic, who are then given an ACEI, may experience severe:
A. Hyperkalemia
B. Hypotension
C. Hepatotoxicity
D. Dysgeusia
E. Neutropenia

Hypotension

13

Renin-Angiotensin-Aldosterone pathways control BP. Renin is released from kidney juxtaglomerular epithelial cells in response to __?__
A. Decreased NaCl to kidney
B. All of the listed answers are correct
C. Decreased blood pressure
D. Decreased intra renal pressure
E. Sympathetic (beta 1) stimulation.

Decreased blood pressure,
Decreased NaCl to kidney
Decreased intra renal pressure
Sympathetic (beta 1) stimulation.
**ALL**

14

Serotonergic drugs (agonists) are incompatible with __?__
A. MAOIs
B. ACEIs
C. DRIs
D. NSAIDs
E. ARBs

MAOIs

15

Which is a 1st generation antihistamine OTC used PO and IV/IM for the treatment of most allergic reactions including anaphylaxis (along with epinephrine); motion sickness; and as an anti-Parkinsonism and anti-extrapyramidal symptoms (EPS) drug. It is usually given PO QID, but no more than q4h and given no more than q6h IV/IM.
A. Chlorpheniramine
B. Fexofenadine
C. Azelastine
D. Diphenhydramine
E. Loratadine

Diphenhydramine (Benadryl)

16

Which is a 2nd generation antihistamine used SID PO to treat symptoms of allergic rhinitis?
A. Promethazine
B. Ondansetron
C. Diphenhydramine
D. Loratadine
E. Chlorpheniramine

Loratadine (Claritin)

17

Which is a 2nd generation antihistamine used to relieve symptoms of seasonal allergic rhinitis and to treat idiopathic urticaria. It is given PO SID or BID
A. Chlorpheniramine
B. Fluoxetine
C. Promethazine
D. Fexofenadine
E. Diphenhydramine

Fexofenadine (Allegra)

18

Which is a 5-PDE inhibitor used PO to treat erectile dysfunction? It is also used to treat pulmonary arterial hypertension.
A. Zileuton
B. Montelukast
C. Enalapril
D. Sildenafil
E. Aprotinin

Sildenafil (Viagra, Revitio)

19

Which is a direct renin inhibitor (DRI)?
A. Misoprostol
B. Montelukast
C. Aliskiren
D. Fluoxetine
E. Buspirone

Aliskiren (Tekturna)

20

Which is a Leukotriene (LT) Receptor blocker given PO SID in the evening for asthma and at any time of day for allergic rhinitis?
A. Misoprostol
B. Captopril
C. Diphenhydramine
D. Dexamethasone
E. Montelukast

Montelukast (Singulair)

21

Which is a LT receptor blocker for asthma, given PO SID an hour before or 2 hours after a meal?
A. Zileuton
B. Benazepril
C. Fexofenadine
D. Ibuprofen
E. Zafirlukast

Zafirlukast (Accolate)

22

Which is a natural proteinase inhibitor obtained from bovine lung? Used IV only to reduce blood loss during cardiac surgery.
A. Zileuton
B. Aprotinin
C. Sildenafil
D. Buspirone
E. Montelukast

Aprotinin (Trasylol)

23

Which is a Prostaglandin E (PGE) analog used to reduce the risk of NSAID induced gastric ulcers? It is given PO QID with food.
A. Buspirone
B. Fluoxetine
C. Montelukast
D. Aliskiren
E. Misoprostol

Misoprostol (Cytotech)

24

Which is Vasotec given PO SID to treat HT and left ventricular dysfunction after MI.
A. Irbesartan
B. Enalapril
C. Valsartan
D. Benazepril
E. Captopril

Enalapril

25

Which is a 1st generation antihistamine OTC used PO q4h-q6h for the temporary relief of respiratory allergy and cold symptoms.
A. Trazodone
B. Fexofenadine
C. Loratadine
D. Azelastine
E. Chlorpheniramine

Chlorpheniramine (Chlor-Trimeton)

26

Which is a 2nd generation antihistamine used as a metered nasal spray and as ophthalmic drops to relieve the symptoms of allergic rhinitis?
A. Azelastine
B. Promethazine
C. Diphenhydramine
D. Benadryl
E. Sumatriptan

Azelastine (Astelin, Optivar)

27

Which is a 5-lipoxygenase (LOX) inhibitor given PO QID for asthma?
A. Zafirlukast
B. Zileuton
C. Diphenhydramine
D. Irbesartan
E. Loratadine

Zileuton (Zyflo)

28

Which is an ACEI given PO SID to treat HT?
A. Benazepril
B. Trazodone
C. Aprotinin
D. Irbesartan
E. Aliskiren

Benazepril (Lotensin)