(15) CV2 SLO Flashcards Preview

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Flashcards in (15) CV2 SLO Deck (23):
1

Adenosine is antagonized by methylxanthines including __?__
A. Phenytoin
B. Furosemide
C. Digoxin
D. Caffeine
E. Dobutamine

Caffeine

2

Digoxin dosages require individualization. Which of the following variables should be taken into account when determining the dose to use?
A. Base dose on Lean body weight
B. Patient’s renal function a factor, base dose on estimated creatinine clearance
C. Age – infants, children and the elderly lower than adults
D. Concomitant diseases or concurrent medications that alter pharmacokinetics (e.g., alter potassium levels)
E. All of the above

All of the above

3

Dobutamine is inactivated by alkaline solutions including __?__
A. Sodium bicarbonate
B. Hydrochloride in gastric juices
C. Plasma
D. Dobutamine is inactive in all the listed solutions
E. Blood

Sodium bicarbonate

4

Which of the following is a Calcium channel blocker (CCB) given PO SID?
A. Nitroglycerin
B. Metoprolol
C. Aliskiren
D. Ranolazine
E. Amlodipine

Amlodipine

5

Which of the following is a CCB given PO SID at bedtime (do not crush for extended release formulation) and TID-QID for other formulations. PO indicated for HTN and angina (all forms of angina) and tachyarrhythmis. An IV (given as injection over 2 minute period) for tachyarrhythmia conversion.
A. Hydralazine
B. Ranolazine
C. Lidocaine
D. Propranolol
E. Verapamil

Verapamil

6

Which of the following is a CCB given PO TID or QID (extended-release capsule – SID), or IV (single bolus or for up to 24 hrs as IV Infusion). The PO form is indicated for HTN & Angina; the IV form is used for tachyarrhythmia control.
A. Propranolol
B. Diltiazem
C. Ranolazine
D. Furosemide
E. Nitroglycerin

Diltiazem

7

Which of the following is a Class 1a Na+ channel blocker anti arrhythmic for ventricular tachyarrhythmias. Avail IM/IV and PO?
A. Propranolol
B. Procainamide
C. Amiodarone
D. Digoxin
E. Adenosine

Procainamide

8

Which of the following is a Class 1b Na+ channel blocker anti arrhythmic for ventricular tachyarrhythmias. Available IV for tachyarrhythmias (and in zillions of other formulations as a topical local anesthetic)?
A. Verapamil
B. Lidocaine
C. Adenosine
D. Amiodarone
E. Propranolol

Lidocaine

9

Which of the following is a Class 1b Na+ channel blocker anti arrhythmic for ventricular tachyarrhythmias? It is available PO as an AED and IV to control arrhythmias.
A. Digoxin
B. Verapamil
C. Amiodarone
D. Propranolol
E. Phenytoin

Phenytoin

10

Which of the following is a Class 1c Na+ channel blocker anti arrhythmic for atrial and ventricular tachyarrhythmias. PO BID, but has a very long t ½ (up to 27 hrs), so steady-state may not be reached for days. Therefore, don’t change dose within 4 days (no more often than every 4 days)?
A. Adenosine
B. Diltiazem
C. Propranolol
D. Digoxin
E. Flecainide

Flecainide

11

Which of the following is a Class III antiarrhythmic? It is available as an IV infusion to control ventricular tachyarrhythmias (high inter-individual variation for dose). PO requires a LOADING dose of around 1 gram/day for 1-3 weeks. Maintenance doses usually SID or BID 400 mg/day.
A. Amiodarone
B. Propranolol
C. Digoxin
D. Adenosine
E. Verapamil

Amiodarone

12

Which of the following is a Class V antiarrhythmic that is only available as an IV only (very short t ½) for acute supraventricular tachycardia?
A. Propranolol
B. Lidocaine
C. Adenosine
D. Phenytoin
E. Diltiazem

Adenosine

13

Which of the following is a Class V antiarrhythmic. It inhibits sodium potassium ATPase and is indicated for mild to moderate HF and atrial fibrillation. Avail PO and IV (can be given IM, but very painful, IV infusion preferred).
A. Diltiazem
B. Verapamil
C. Propranolol
D. Digoxin
E. Lidocaine

Digoxin

14

Which of the following is a pFOX (partial fatty acid oxidase) inhibitor for chronic angina?
A. Ranolazine
B. Verapamil
C. Nitroglycerin
D. Diltiazem
E. Amlodipine

Ranolazine

15

Which of the following is a short acting nitrate vasodilator indicated for typical angina or MI? It is available in PO, transdermal, IV, topical formulations.
A. Diltiazem
B. Verapamil
C. Nitroglycerin
D. Amlodipine
E. Ranolazine

Nitroglycerin

16

Which of the following is an rDNA form of human B-type natriuretic peptide given IV as a treatment for acute decompensated heart failure?
A. Procainamide
B. Dobutamine
C. Milrinone
D. Furosemide
E. Nesiritide

Nesiritide

17

__?__ , is associated with numerous serious ADRs including CV collapse secondary to bradycardia and hypotension, blood dyscrasias including Purple Glove Syndrome, drug-induced Lupus, muscle twitches including nastigmus, osteomalacia and connective tissue changes, and SJS.
A. Propranolol
B. Diltiazem
C. Phenytoin
D. Ranolazine
E. Digoxin

Phenytoin

18

__?__ is a Loop diuretic available PO and IV/IM. It is indicated PO for edema and HTN. PO dosage must be individualized and usually only given 2-4 days/week SID or BID, but not more often than QID. The IV/IM formulation should only be used in patients unable to take the PO form. The IV must be given slowly to avoid hearing loss.
A. Natrecor
B. Primacor
C. Lasix
D. Novaplus
E. Aldactone

Lasix

19

Furosemide will increase the likelihood of digoxin toxicity because it causes the loss of __?__
A. Hearing
B. Weight
C. Vision
D. Potassium
E. Calcium

Potassium

20

The Class V antiarrhythmic __?__ is associated with arrhythmias, hypotension, nausea, heartburn, flushing, edema, head ache, fatigue, and halo vision. The risk of toxicity with this drug is increased by low plasma potassium or magnesium as occurs during therapy with diuretics.
A. Amiodarone
B. Digoxin
C. Phenytoin
D. Diltiazem
E. Propranolol

Digoxin

21

Which of the following is a 3-phosophodiesterase inhibitor (3-PDE) positive inotropic agent given IV (infusion) as a short-term treatment for acute decompensated heart failure?
A. Milrinone
B. Procainamide
C. Furosemide
D. Nesiritide
E. Dobutamine

Milrinone

22

__?__ is a synthetic catecholamine available as a solution that may be given PO or as an IV infusion to treat cardiac decompensation (heart failure) on a short-term basis.
A. Ranolazine
B. Verapamil
C. Dobutamine
D. Furosemide
E. Milrinone

Dobutamine

23

__?__ are associated with severe headache, flushing, hypotension and reflex tachycardia. Tolerance to the vasodilation effects is common, but can be overcome by spacing doses 10-12 hours apart.
A. Beta Blockers
B. CCBs
C. Nitrate and nitrite vasodilators
D. Diuretics
E. Methyl xanthines like caffeine

Nitrate and nitrite vasodilators