(20) Micro 4 SLO Flashcards Preview

Pharmacology > (20) Micro 4 SLO > Flashcards

Flashcards in (20) Micro 4 SLO Deck (15):
1

Chloroquine (Aralen) is very toxic to __?__
A. None of the listed answers, Chloroquine is very safe
B. All the listed answers are correct
C. Patients older than 60 years
D. Crohn’s patients
E. Kids

Kids

2

Metronidazole (and Tinidazole) are associated with __?__
A. A Disulfiram-like reaction with alcohol, decreased seizure threshold, peripheral neuropathy, increased risk of cancer especially in Crohn’s patients. Causes a metallic taste in the mouth.
B. Tooth discoloration (in developing permanent teeth) and severe photosensitivity.
C. They are not associated with any of these effects
D. An increased risk of seizures, psychosis, vivid dreams, hallucinations, and photosensitization
E. Tendon rupture, photosensitivity, CDAD, creating resistant bacterial species, nightmares, tachycardia, and peripheral neuropathies.

A Disulfiram-like reaction with alcohol, decreased seizure threshold, peripheral neuropathy, increased risk of cancer especially in Crohn’s patients. Causes a metallic taste in the mouth

3

Metronidazole and Tinidazole work by:
A. Interfering with metabolism (which interfers with DNA/RNA synthesis)
B. Another, not listed, mechanism
C. Inhibiting cell wall synthesis
D. Blocking protein synthesis
E. Inhibiting cell wall formation

Interfering with metabolism (which interfers with DNA/RNA synthesis)

4

Metronidazole increases the risk of breast and colon cancer in __?__
A. Cancer patients
B. Kids
C. Patients with a seizure history
D. Crohn’s patients
E. Pregnant patients

Crohn’s patients

5

Metronidazole may cause psychosis in alcoholics taking __?__
A. Corticosteroids
B. Warfarin
C. Disulfiram
D. Doxycycline
E. Aspirin

Disulfiram

6

Nitazoxanide is __?__
A. Only given by IV infusion
B. A Prodrug, metabolized by and mostly excreted by the liver
C. Metabolized in the lungs
D. Not metabolized
E. Not well absorbed

A Prodrug, metabolized by and mostly excreted by the liver

7

Tetracyclines work by:
A. Interfering with DNA synthesis
B. Inhibiting cell wall formation
C. Blocking protein synthesis
D. None of the listed mechanisms
E. Interfering with metabolism

Blocking protein synthesis

8

The antimalarial quinolones (Chloroquine and Mefloquine) are associated with__?__.
A. A Disulfiram-like reaction with alcohol, decreased seizure threshold, peripheral neuropathy, increased risk of cancer especially in Crohn’s patients. Causes a metallic taste in the mouth.
B. An increased risk of seizures, psychosis, vivid dreams, hallucinations, and photosensitization
C. Tendon rupture, photosensitivity, CDAD, creating resistant bacterial species, nightmares, tachycardia, and peripheral neuropathies.
D. 8th cranial nerve damage
E. Tooth discoloration (in developing permanent teeth) and severe photosensitivity.

An increased risk of seizures, psychosis, vivid dreams, hallucinations, and photosensitization

9

The tetracyclines are associated with __?__
A. Tooth discoloration (in developing permanent teeth) and severe photosensitivity.
B. Liver failure
C. Tendon rupture.
D. An increased risk of psychosis
E. A metallic taste in the mouth.

Tooth discoloration (in developing permanent teeth) and severe photosensitivity.

10

Which is a quinolone antiprotozoal for amoeba and malaria?
A. Doxycycline (Vibramycin)
B. Ciprofloxacin (Cipro)
C. Chloroquine (Aralen)
D. Metronidazole (Flagyl)
E. Mefloquine (Lariam)

Chloroquine (Aralen)

11

Which is a quinolone antiprotozoal that is only indicated for malaria?
A. Metronidazole (Flagyl)
B. Doxycycline (Vibramycin)
C. Ciprofloxacin (Cipro)
D. Mefloquine (Lariam)
E. Chloroquine (Aralen)

Mefloquine (Lariam)

12

Which is an antiprotozoal for amoeba and trichomonas; an antibacterial for anaerobic bacteria including Clostridium difficile; and is used to treat Rosacea?
A. Doxycycline (Vibramycin)
B. Metronidazole (Flagyl)
C. Chloroquine (Aralen)
D. Mefloquine (Lariam)
E. Ciprofloxacin (Cipro)

Metronidazole (Flagyl)

13

Which is indicated as an antiprotozoal for amoeba, giardia, trichomonas, and antibacterial for bacterial vaginosis in non-pregnant women?
A. Tinidazole (Tindamax)
B. Nitazoxanide (Alinia)
C. Chloroquine (Aralen)
D. Ciprofloxacin (Cipro)
E. Mefloquine (Lariam)

Tinidazole (Tindamax)

14

Which is the only FDA approved antiprotozoal for cryptosporidiosis?
A. Nitazoxanide (Alinia)
B. Doxycycline (Vibramycin)
C. Chloroquine (Aralen)
D. Metronidazole (Flagyl)
E. Mefloquine (Lariam)

Nitazoxanide (Alinia)

15

Which is a tetracycline antibiotic with many indications, including for amoeba, malaria, rickettsia, and spirochete bacteria including Lyme and Leptospirosis?
A. Mefloquine (Lariam)
B. Ciprofloxacin (Cipro)
C. Metronidazole (Flagyl)
D. Chloroquine (Aralen)
E. Doxycycline (Vibramycin)

Doxycycline (Vibramycin)