(7) PNS SLO Flashcards Preview

Pharmacology > (7) PNS SLO > Flashcards

Flashcards in (7) PNS SLO Deck (20):
1

Alpha 1 and 2 Agonists like Oxymetazoline and Phenylephrine are associated with: ?
A. Malignant hyperthermia
B. Rebound angina
C. Rebound bronchoconstriction
D. Tachycardia and serotonin syndrome
E. Tissue necrosis

Tachycardia and seritonin syndrome

2

Alpha 1 ANTagonists like Doxazosin and Tamulosin are associated with: ?
A. Malignant hyperthermia
B. Hypotension, priapism and arrhythmias
C. Tachycardia, lowered seizure threshold, hyperglycemia
D. Extravasation leads to tissue necrosis
E. Increased blood pressure in the kidney leading to kidney failure

Hypotension, priapism and arrhythmias

3

Alpha 2 Agonist (Clonidine) is associated with: ?
A. Decreased blood pressure in the kidney leading to renin release
B. Malignant hyperthermia
C. Extravasation leads to tissue necrosis
D. Tachycardia, lowered seizure threshold, hyperglycemia
E. Hypotension, withdrawal syndrome that includes rebound, severe hypertension

Hypotension, withdrawal syndrome that includes rebound, severe hypertension

4

Antimuscarinics like Atropine are associated with: ?
A. Tachycardia, lowered seizure threshold, hyperglycemia
B. Withdrawal syndrome, masking hyperthyroid and hypoglycemia symptoms
C. Inability to sweat, Constipation
D. Hypotension, withdrawal severe hypertension
E. Bradycardia with reflex tachycardia, diarrhea

Inability to sweat, constipation

5

Beta 2 Agonists like Albuterol are associated with: ?
A. Hypotension, withdrawal severe hypertension
B. Inability to sweat, Constipation
C. Withdrawal syndrome, masking hyperthyroid and hypoglycemia symptoms
D. Bradycardia with reflex tachycardia, diarrhea
E. Tachycardia, lowered seizure threshold, hyperglycemia

Tachycardia, lowered seizure threshold, hyperglycemia

6

Mixed Beta Agonist (Isoproterenol) are associated with: ?
A. Tachycardia, lowered seizure threshold, hyperglycemia
B. Extravasation that leads to tissue necrosis
C. Decreased blood pressure in the kidney leading to renin release
D. Malignant hyperthermia
E. Hypotension, withdrawal severe hypertension

Decreased BP in the kidneys leading to renin release

7

Salmeterol can cause a fatal bronchoconstriction in sensitive individuals. What must now be added to Salmeterol to off set this effect?
A. An antimuscarinic (e.g., atropine)
B. A corticosteroid (e.g., fluticasone)
C. A beta 2 agonist (e.g., albuterol)
D. A muscarinic agonist (e.g., bethanechol)
E. A beta antagonist (e.g., propranolol)

Corticosteroid (e.g. Fluticasone)

8

Salmeterol can cause potentially fatal __?__ - because 1/6 of the population have hypersensitive receptors (boxed warning)
A. Blood dyscrasias
B. Tachycardia
C. Bleeding
D. Psychosis
E. Rebound bronchoconstriction

Rebound bronchoconstriction

9

The depolarizing NMJB Succinylcholine is associated with: ?
A. Rebound bronchoconstriction
B. Decreased blood pressure in the kidney leading to renin release
C. Hypotension, withdrawal severe hypertension
D. Hyperglycemia and diabetic coma
E. Malignant hyperthermia

Malignant hyperthermia

10

The Mneumonic:? red as a beat (vasodilation), hot as a poker, dry as a bone (no secretions, constipation) mad at a hatter, beating like a hart (Tachycardia), blind as a bat (no accommodation, dilated pupils)
A. Anticholinergic or antimuscarinic poisoning or overdose (example: OD on atropine)
B. Mixed alpha and beta sympathomimetic toxicity (example: OD on Epinephrine)
C. Alpha sympathomimetic toxicity (example: OD of Oxymetazoline)
D. Beta sympathomimetic toxicity (example: OD on Albuterol)
E. Anti Acetylcholinesterase poisoning (example: OD on Donepezil)

ANTIcholinergic or ANTImuscarinic poisoning or OD
Example: OD on Atropine

11

The non-polarizing NMJB Pancuronium is associated with: ?
A. Bradycardia
B. Rebound angina
C. Tachycardia due to a vagalytic effect
D. Decreased blood pressure in the kidney leading to renin release
E. Bronchoconstriction

Tachycardia due to vagalytic effects

12

Which is a Beta 2 Agonist indicated as a short-acting bronchodilator for asthma?
A. Metoprolol
B. Terbutaline
C. Labetalol
D. Phentolamine
E. Doxazosin

Terbutaline (Brethaire)

13

What is a catecholamine and a mixed Alpha and Beta Agonist for shock?
A. Pancuronium
B. Scopolamine
C. Dobutamine
D. Dopamine
E. Neostigmine

Dopamine

14

What is a long-acting Beta 2 Agonist (LABA) bronchodilator for asthma and COPD?
A. Terbutaline
B. Labetalol
C. Salmeterol
D. Albuterol
E. Isoproterenol

Salmeterol (Serevent, Advair)

15

What is a topical Alpha 1 & 2 Agonist indicated as a nasal decongestant for cold and allergy symptoms that has a strong rebound effect when discontinued?
A. Phenylephrine
B. Clonidine
C. Epinephrine
D. Oxymetazoline
E. Norepinephrine

Oxymetazoline (Afrin)

16

What Alpha 1 & 2 Agonist used mainly as a nasal decongestant for cold & allergy can also be used to treat shock and hemorrhoids?
A. Propranolol
B. Phentolamine
C. Oxymetazoline
D. Atropine
E. Phenylephrine

Phenylephrine (Neo-synephrine)

17

What is an Alpha 1 & 2 ANTagonist used to protect against tissue necrosis when catecholamines are extravasated, the diagnose pheochromocytoma and to treat the hypertensive crisis in pheochromacytoma?
A. Phentolamine
B. Tamsulosin
C. Labetalol
D. Metoprolol
E. Doxazosin

Phentolamine (Regetine, Oraverse)

18

What Alpha 1 ANTagonist is indicated only for BPH?
A. Metoprolol
B. Tamsulosin
C. Labetalol
D. Oxymetazoline
E. Phentolamine

Tamulosin (Flomax)

19

Which Alpha 2 Agonist is indicated for HT, chronic pain, alcohol & opiate withdrawal and has many off-label uses?
A. Epinephrine
B. Clonidine
C. Phenylephrine
D. Norepinephrine
E. Oxymetazoline

Clonidine (Catapres)

20

Which of the following is a Beta 2 agonist indicated as a short-acting bronchodilator for asthma?
A. Isoproterenol
B. Propranolol
C. Atenolol
D. Albuterol
E. Salmeterol

Albuterol