1.4 Innate Immunity Lec 1

Question 1

Eosinophil stains ____ with Wright’s stain?

Answer 1

red

Question 2

Eosinophils are in high or low levels in blood?

Answer 2

low

Question 3

Eosinophil can or cannot interact with antibodies? phagocytic or not?

Answer 3

CAN interact with antibodies therefore they can be phagocytic

Question 4

Eosinophil are important for?

Answer 4

worm and parasitic infections

Question 5

elevated levels of eosinophils are associated with?

Answer 5

allergies or asthma

Question 6

Eosinophil granules contain?

Answer 6

• Eosinophil cationic protein
• Major basic protein
• Eosinophil peroxidase

Question 7

with Wright’s stain, Basophils are what color?

Answer 7

dark blue

Question 8

Basophils are in high or low levels in blood?

Answer 8

low

Question 9

Basophils contain ____-filled granules

Answer 9

histamine-filled granules

Question 10

Basophils activation is important in? Promotes?

Answer 10

important in allergies

*Promotes inflammation

Question 11

Mast cells are related to?

Answer 11

basophils

Question 12

Mast cells stain?

Answer 12

dark blue in wright’s stain

Question 13

where are Mast cells found?

Answer 13

in tissues

Question 14

Mast cells contain ____-filled granules? important in??

Answer 14

histamine-filled granules

*important in allergy symptoms

Question 15

Two types of mast cells?

Answer 15

1) connective tissue mast cell

2) mucosal mast cell

Question 16

monocytes are part of what system?

Answer 16

part of reticuloendothelial system

Question 17

are monocytes a macrophage?

Answer 17

yes!

Question 18

each macrophage/monocyte has a _____ nucleus? EXCEPT?

Answer 18

bilobed

*Except for osteoclast each macrophage is phagocytic

Question 19

Monocyte-macrophages present antigens to?

Answer 19

T-cells

Question 20

Monocyte-macrophages can opsonize?

Answer 20

antibody-bound antigens

Question 21

monocytes of blood develop into ______ at inflammation?

Answer 21

Inflammatory macrophage

Question 22

monocytes of blood develop into ______ in liver?

Answer 22

Kupffercells

Question 23

monocytes of blood develop into ______ in lungs?

Answer 23

alveolar macrophages

Question 24

monocytes of blood develop into ______ in spleen?

Answer 24

splenic macrophages

Question 25

monocytes of blood develop into ______ in brain?

Answer 25

microglial

Question 26

monocytes of blood develop into ______ in bone?

Answer 26

osteoclasts

Question 27

monocytes of blood develop into ______ macrophages?

Answer 27

peritoneal macrophages