abx IV Flashcards by tcarlso 3

What is the treatment of choice of uncomplicated soft tissue infections? What is there is an allergy to these agents? What about if hospitalized?

PCN
1st gen ceph

If allergy = vanco

If hospitalized = nafcillin or cfazolin

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What is the treatment for complicated skin and soft tissue infection?

PCN + lactamase inhibitor

Carbapenem

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What is the treatment for MRSA skin infections?

Vanco
Linezolid
Daptomycin

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What are ‘uncomplicated” skin/soft tissue infections cause by?

Staph aureus or strep pyogenes

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What are the complicated skin infections caused by?

MRSA or e.coli/pseudomonas

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What is the anti-pseudomonal abx?

Ticarcillin

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What is the empiric treatment for osteomyelitis?

Vanco

Cephalosporins

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What is the treatment for bone/joint infections secondary to surgery?

PCN + lactamase inhibitor

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What is the empiric treatment for septic arthritis? What if MRSA?

Ceftriaxone

Vanco, linezolid or daptomycin

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What is the treatment for prosthetic joint infection?

Rifampin

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What is the abx of choice for chronic osteomyelitis?

Organism dependent

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What is the abx of choice for hospitalization for osteomyelitis?

IV nafcillin or cefazolin

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What is the most common causeative organism with osteomyelitis?

S aureus or staph

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Infections following orthopedic surgeries are often caused by what?

E.coli or pseudomonas

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Septic arthritis is usually caused by what organism?

S aureus s.proenes
Strep pneumo
N. gonn

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Protehstic joint infections are usually caused by what

S aureus

Staph

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What is the abx for acute sinusitis?

Amox + clavulanate

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What is the treatment for chronic bronchitis?

Amox + clavulanate

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What is the treatment for pharyngitis?

PCN or amox

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What are the most common organisms causing URTs?

S pneumo
H. influenzae
moarell catarrhalis

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What are the causes of acute exacerbation of chronic bronchitis?

H. influenzae
S. pneumoniae
M. Catarrhalis

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The most common cause of acute bacteria pharyngitis for adults and kids is what?

Strep

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What are the three abx of choice for ambulatory, community acquired pneumonia?

Erythromycin
Azithromycin
Clarithromycin

What is the abx of choice for hospitalization pneumonia?

Beta lactam + macrolide

What is the treatment for MRSA pneumonia?

Vanco or linezolid

What is the empiric treatment for hospital acquired pneumonia?

Ceftriaxone

What is the most common cause of pneumonia?

Strep penumoniae and mycoplasma pneumonia

What are the most common causes of hospitalized pneumonia?

gram negative bacilli such as Klebsiella, E.coli, enterobacter, serratia, pseudomonas, acintobacter

***something about cell wall***

***

What is the abx of choice for uncomplicated cystitis?

Trimethoprim/sulfa

What is the treatment for pyelonephritis?

TMP-SMX and/or fluoroquinolone

What is the most common cause of UTIs?

E.coli

What is the treatment for complicated UTIs?

Fluoroquinolones | TMP-SMX

What is the abx of choice for prostatitis?

Fluoroquinolones | TMP-SMX

What are the causes of complicated UTIs?

S aureus | abx resistant gram - baccili

Acute/chronic prostatitis is caused by what?

``` e. coli Proteus Klebsiella Pseudomonas Enterococcus ```

What are the intra-abdominal infections abx treatment choice?

Ticarcillin | Clavulanate

What is the treatment for C.diff?

Metronidazole if mild-moderate Vanco - if severe

What are the common causes of intra-abdominal infections?

E. coli Klebsiella Proteus Bacteroides

What type of bacteria usually infect the GI Tract?

Gram -

What is the most common cause of abx-associated diarrhea?

C.diff

What are the abx that are commonly associated with causing C.diff?

Fluoroquinolones Clindamycin Cephalosporins

What is the abx of choice for community acquired meningitis >2 months old?

Ceftriaxone of ceftaxime + vanco

What is the treatment of choice for neonatal meningitis?

Ampicillin + cephalosporin + gentamycin

What is the most common cause of community acquired meningitis in adults and children? (2)

S. pneumoniae | N. Meningitidis

Neonatal meningitis is most often caused by what? (3)

GBS Gram neg organisms Listeria monocytogenes

Ready-to-eat meats bacteria = ? How does this relate to neonate meningitis

Listeria monocytogenes This can cause neonate meningitis if prego mother eats these

What is the empiric treatment for sepsis?

Cefepime + vanco

What is the empiric treatment for endocarditis?

Ceftriaxone + vanco

What are the abx for empiric treatment of fever and neutropenia?

Cipro + amox/clavulanate

Bacterial endocarditis is usually caused by what?

Staph or strep

Infectious fever and neutropenia is most commonly caused by what?

Gram + bacteria

What are the three abx of choice for drug resistant enterococci?

Linezolid Daptomycin Tigecycline

What is the treatment for gram negative multidrug resistant bacteria?

Carbapenem (imipenem or meropenem)

What is the treatment for gram negative multidrug resistant bacteria that have carbapenemases?

Polymyxin B | Tigecycline

Many strains of enterococcus are resistant to what abx?

Ampicillin Gentamicin Streptomycin Vancomycin

What is the MOA of pseudomonas bacteria resistance?

Beta lactamases