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Flashcards in Introduction Deck (30)
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1
Q

What are pharmacokinetics?

A

a division of pharmacology focused on processes that affect drug concentration in the body. These processes include absorption, distribution, metabolism and elimination

2
Q

What are pharmacodynamics?

A

on how a drug produces an effect

3
Q

What is toxicology?

A

It focuses on the harmful effects of drugs and other chemicals and on the mechanisms by which toxic agents produce pathological changes

4
Q

What is pharmacy?

A

the science and profession concerned with the preparation, storage, dispensing, and proper utilization of drug products

5
Q

Which drug schedule: High abuse potential, no medical use

A

Schedule I

6
Q

Which drug schedule: high abuse potential, have a medical use, potential for psychological and physical dependence

A

Schedule II

7
Q

Which drug schedule: Less abuse potential, have a medical use, low potential for physical dependence, but high dependence for psychological dependence

A

Schedule III

8
Q

Which drug schedule: have a medical use, little potential of dependence

A

Schedule Iv

9
Q

Which drug schedule: have a medical use, limited dependence

A

Schedule V

10
Q

What level of government decides who can prescribe drugs?

A

State level

11
Q

What level of government decides which drugs are prescription vs not?

A

Federal level

12
Q

All prescription drugs are controlled by what governmental body?

A

USFDA

13
Q

Antihistamines should never be combined with what?

A

Alcohol, or other depressants

14
Q

What is the active ingredient in dramamine?

A

Dimenhydrinate

15
Q

What is the active ingredient in Benadryl?

A

Diphenhydramine

16
Q

What are the three steps of drug development?

A
  1. Identification of a new drug
  2. Experimentation
  3. Clinical testing
17
Q

What do toxicity studies investigate?

A

No effect dose
Minimum lethal dose
Effective dose

18
Q

What is involved in phase I testing of a drug?

A

Safe dosing range with a small amount of pts

19
Q

What is involved in phase II testing of a drug?

A

Testing the drug with a relatively small number of patients to determine if the drug actually works

20
Q

What is involved in phase III testing of a drug?

A

Larger phase II to test statistical significance

21
Q

What is involved in phase IV testing of a drug?

A

Continued monitoring during actual clinical use

22
Q

What are the two contraindications to dopamine administration?

A

MAOIs

TCAs

23
Q

What are the effects of dopamine at low, moderate, and high doses?

A

Diuresis
Tachycardia
HTN

24
Q

What are the effects of epi at low, moderate, and high doses?

A

beta 1

***

25
Q

What is the MOA of guanidine?

A

competes with NE for reuptake via NET1

26
Q

Blocking H2 can result in what?

A

Hypotension

27
Q

What is the indication for alvimopan?

A

Post op

28
Q

What is the indication for methylnaltrexone?

A

Hospice pts on opioids

29
Q

Which of the mu opioid agonist is laced with atropine

A

Diphenoxylate

30
Q

What are the two receptors in the semicircular canals?

A

H1

M1