First aid drugs test 3 Flashcards Preview

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Flashcards in First aid drugs test 3 Deck (71):
1

What is the MOA of ethosuximide, and what is it used to treat?

Ca channel blocker
Absence seizures

2

What is the MOA of benzodiazepines as antiepileptics? What type of seizures are these used to treat? Which of the two benzos are used to treat this?

GABA-(A) agonists
Treats status epilepticus
Diazepam and lorazepam

3

What is the MOA of phenytoin? What type of seizures is it used to treat?

Na channel blocker
Simple, complex, tonic/clonic, and status epilepticus

4

What is the MOA of carbamazepine? What type of seizures is it used to treat?

Na channel blocker
Simple, complex, and tonic clonic

5

What is the MOA of valproic acid? What type of seizures is it used to treat?

Na channel blocker and GABA transaminase inhibitor
Simple, complex, tonic clonic, and absent

6

What is the MOA of gabapentin? What type of seizures is it used to treat?

Ca channel blocker
Simple, complex, tonic/clonic

7

What is the MOA of phenobarbital? What type of seizures is it used to treat?

Increase GABA-(A) channel open duration
Simple, complex, tonic/clonic

8

What is the MOA of Topiramate? What type of seizures is it used to treat?

Na channel blocker
simple, complex, tonic/clonic

9

What is the MOA of Lamotrigine? What type of seizures is it used to treat?

Na channel blocker
All szs except tonic/clonic

10

What is the MOA of Tiagabine? What type of seizures is it used to treat?

Inhibit GABA reuptake
Simple and complex seizures

11

What is the MOA of Vigabatrin? What type of seizures is it used to treat?

Irreversible inhibitor of GABA transaminase
simple and complex

12

What are the drugs used to treat simple seizures? Complex?

All antiepileptics except ethosuximide and benzos

13

What are the drugs used to treat tonic/clonic seizures?

All antiepileptics except Ethosuximide, Benzos, tiagabine and vigabatrin

14

What are the drugs used to treat absence seizures (3)?

Ethosuximide
Valproic acid
Lamotrigine

15

What are the drugs used to treat status epilepticus (2)?

Benzos
Phenytoin

16

Chlorpromazine

Typical antipsychotic

17

Thioridazine

Typical antipsychotic

18

Fluphenazine

Typical antipsychotic

19

Haloperidol

Typical antipsychotic

20

Clozapine

Atypical antipsychotic

21

Olanzapine

Atypical antipsychotic

22

Risperidone

Atypical antipsychotic

23

Aripiprazole

Atypical antipsychotic

24

Quetiapine

Atypical antipsychotic

25

Ziprasidone

Atypical antipsychotic

26

What is the MOA and use of: Moclobemide

MAO-A inhibitor

27

What is the MOA and use of: memantine

Ca channel blocker, Glutamate inhibitor (NMDA antagonist to treat AD

28

What is the MOA and use of: Meprobamate

Sedative given prior to surgery (Benzo-like)

29

What is the MOA and use of: Ropinirole

Dopamine receptor agonist used in the treatment of Parkinson's

30

What is the MOA and use of: Amantadine

antiviral given for PD. Unknown MOA

31

What is the MOA and use of: Trihexyphenidyl

M2 blocker used for the treatment of Parkinson's treatment

32

What is the MOA and use of: Pramiprexole

Dopamine receptor agonist used in PD

33

What is the MOA and use of: Apomorphine

Dopamine receptor agonist used in PD when L-DOPA doesn't work anymore

34

What is the MOA and use of: Rasagiline

MAO-B inhibitor for PD

35

What is the MOA and use of: Atomoxetine

NE reuptake inhibitor used in the treatment of ADHD

36

What is the MOA and use of: Modafinil

Histamine receptor agonist used to increase wakefulness in epileptic patients

37

What is the MOA and use of: Pentylenetetrazol

GABA-(A) antagonist used as a respiratory stimulant

38

What is the MOA and use of: Fomepizole

Alcohol dehydrogenase inhibitor, used in the treatment of methanol ingestion

39

What is the MOA and use of: Disulfram

Acetaldehyde dehydrogenase inhibitor, used in the treatment of alcoholism d/t causing adverse side effects of acetaldehyde buildup (N/v, flushing)

40

What is the MOA and use of: Retigabine

Potassium channel opener, anticonvulsant

41

What is the MOA and use of: Mirtazapine

Alpha-2 antagonist used in the treatment of depression, causing increased release of catecholamines

42

What is the MOA and use of: Felbamate

Na and Glutamine antagonist used for anticonvulsant

43

What is the MOA and use of: Topiramate

Anticonvulsant

Na and Ca channel blocker, potentiates GABA

44

What is the MOA and use of: Benztropine

M receptor antagonist used in PD

45

What is the MOA and use of: Duloxtine

SNRI, depression and chronic pain

46

What is the MOA and use of: Trazodone

5HT2 antagonist, hypnotic

47

What are the two anticonvulsants used to treat myotonic seizures?

Clonazepam
Valproic acid

48

What is the sedative that can be used safely in pregnant women

Phenobarbital

49

What is the MOA and use of: Primidone

Converted into phenobarbital in the liver (sedative)

50

What is the major adverse reaction with halothane

Hepatitis

51

What are the advantages and disadvantages of sevoflurane

Fast onset, potent, not as irritating to the lungs

Kidney and hepatic damage

52

What is the major downside of propofol

Decreased CO

53

What is the major downside of Enflurane

CNS stimulant
Pungent odor

54

What are the two pungent Halogenated agents?

Enflurane
Isoflurane

55

Which halogenated agent should not be given to a pt with a h/o smoking or COPD? Why?

Desflurane
Airway irritant

56

What is the ideal halogenated agent?

Sevoflurane

57

Which opioid analgesic has a severe reaction with MAOIs? Why?

Meperidine--5HT reuptake inhibition will cause serotonin syndrome

58

Which type of local anesthetic produces PABA as a byproduct?

Esters

59

Which two atypical antipsychotics are associated with weight gain?

Clonazapine
Olanzapine

60

Which atypical antipsychotic causes tardive dyskinesia?

Risperidone

61

Which type of antipsychotics have more active metabolites: Typical or atypical

Atypical

62

Which amino acids interfere with L-DOPA absorption?

Leucine and isoleucine

63

Short, medium, or long acting: triazolam

Short

64

Short, medium, or long acting: lorazepam

Medium

65

Short, medium, or long acting: oxazepam

Medium

66

Short, medium, or long acting: temazepam

Medium

67

Short, medium, or long acting: alprazolam

Medium

68

Short, medium, or long acting: Clorazepate

Long

69

Short, medium, or long acting: Diazepam

Long

70

Short, medium, or long acting: Chlordiazepoxide

Long

71

Short, medium, or long acting: flurazepam

Long