First aid drugs test 3 Flashcards by tcarlso 3

What is the MOA of ethosuximide, and what is it used to treat?

Ca channel blocker

Absence seizures

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What is the MOA of benzodiazepines as antiepileptics? What type of seizures are these used to treat? Which of the two benzos are used to treat this?

GABA-(A) agonists
Treats status epilepticus
Diazepam and lorazepam

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What is the MOA of phenytoin? What type of seizures is it used to treat?

Na channel blocker

Simple, complex, tonic/clonic, and status epilepticus

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What is the MOA of carbamazepine? What type of seizures is it used to treat?

Na channel blocker

Simple, complex, and tonic clonic

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What is the MOA of valproic acid? What type of seizures is it used to treat?

Na channel blocker and GABA transaminase inhibitor

Simple, complex, tonic clonic, and absent

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What is the MOA of gabapentin? What type of seizures is it used to treat?

Ca channel blocker

Simple, complex, tonic/clonic

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What is the MOA of phenobarbital? What type of seizures is it used to treat?

Increase GABA-(A) channel open duration

Simple, complex, tonic/clonic

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What is the MOA of Topiramate? What type of seizures is it used to treat?

Na channel blocker

simple, complex, tonic/clonic

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What is the MOA of Lamotrigine? What type of seizures is it used to treat?

Na channel blocker

All szs except tonic/clonic

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What is the MOA of Tiagabine? What type of seizures is it used to treat?

Inhibit GABA reuptake

Simple and complex seizures

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What is the MOA of Vigabatrin? What type of seizures is it used to treat?

Irreversible inhibitor of GABA transaminase

simple and complex

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What are the drugs used to treat simple seizures? Complex?

All antiepileptics except ethosuximide and benzos

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What are the drugs used to treat tonic/clonic seizures?

All antiepileptics except Ethosuximide, Benzos, tiagabine and vigabatrin

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What are the drugs used to treat absence seizures (3)?

Ethosuximide
Valproic acid
Lamotrigine

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What are the drugs used to treat status epilepticus (2)?

Benzos

Phenytoin

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Chlorpromazine

Typical antipsychotic

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Thioridazine

Typical antipsychotic

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Fluphenazine

Typical antipsychotic

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Haloperidol

Typical antipsychotic

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Clozapine

Atypical antipsychotic

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Olanzapine

Atypical antipsychotic

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Risperidone

Atypical antipsychotic

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Aripiprazole

Atypical antipsychotic

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Quetiapine

Atypical antipsychotic

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Ziprasidone

Atypical antipsychotic

What is the MOA and use of: Moclobemide

MAO-A inhibitor

What is the MOA and use of: memantine

Ca channel blocker, Glutamate inhibitor (NMDA antagonist to treat AD

What is the MOA and use of: Meprobamate

Sedative given prior to surgery (Benzo-like)

What is the MOA and use of: Ropinirole

Dopamine receptor agonist used in the treatment of Parkinson's

What is the MOA and use of: Amantadine

antiviral given for PD. Unknown MOA

What is the MOA and use of: Trihexyphenidyl

M2 blocker used for the treatment of Parkinson's treatment

What is the MOA and use of: Pramiprexole

Dopamine receptor agonist used in PD

What is the MOA and use of: Apomorphine

Dopamine receptor agonist used in PD when L-DOPA doesn't work anymore

What is the MOA and use of: Rasagiline

MAO-B inhibitor for PD

What is the MOA and use of: Atomoxetine

NE reuptake inhibitor used in the treatment of ADHD

What is the MOA and use of: Modafinil

Histamine receptor agonist used to increase wakefulness in epileptic patients

What is the MOA and use of: Pentylenetetrazol

GABA-(A) antagonist used as a respiratory stimulant

What is the MOA and use of: Fomepizole

Alcohol dehydrogenase inhibitor, used in the treatment of methanol ingestion

What is the MOA and use of: Disulfram

Acetaldehyde dehydrogenase inhibitor, used in the treatment of alcoholism d/t causing adverse side effects of acetaldehyde buildup (N/v, flushing)

What is the MOA and use of: Retigabine

Potassium channel opener, anticonvulsant

What is the MOA and use of: Mirtazapine

Alpha-2 antagonist used in the treatment of depression, causing increased release of catecholamines

What is the MOA and use of: Felbamate

Na and Glutamine antagonist used for anticonvulsant

What is the MOA and use of: Topiramate

Anticonvulsant Na and Ca channel blocker, potentiates GABA

What is the MOA and use of: Benztropine

M receptor antagonist used in PD

What is the MOA and use of: Duloxtine

SNRI, depression and chronic pain

What is the MOA and use of: Trazodone

5HT2 antagonist, hypnotic

What are the two anticonvulsants used to treat myotonic seizures?

Clonazepam | Valproic acid

What is the sedative that can be used safely in pregnant women

Phenobarbital

What is the MOA and use of: Primidone

Converted into phenobarbital in the liver (sedative)

What is the major adverse reaction with halothane

Hepatitis

What are the advantages and disadvantages of sevoflurane

Fast onset, potent, not as irritating to the lungs Kidney and hepatic damage

What is the major downside of propofol

Decreased CO

What is the major downside of Enflurane

CNS stimulant | Pungent odor

What are the two pungent Halogenated agents?

Enflurane | Isoflurane

Which halogenated agent should not be given to a pt with a h/o smoking or COPD? Why?

Desflurane | Airway irritant

What is the ideal halogenated agent?

Sevoflurane

Which opioid analgesic has a severe reaction with MAOIs? Why?

Meperidine--5HT reuptake inhibition will cause serotonin syndrome

Which type of local anesthetic produces PABA as a byproduct?

Esters

Which two atypical antipsychotics are associated with weight gain?

Clonazapine | Olanzapine

Which atypical antipsychotic causes tardive dyskinesia?

Risperidone

Which type of antipsychotics have more active metabolites: Typical or atypical

Atypical

Which amino acids interfere with L-DOPA absorption?

Leucine and isoleucine

Short, medium, or long acting: triazolam

Short

Short, medium, or long acting: lorazepam

Medium

Short, medium, or long acting: oxazepam

Medium

Short, medium, or long acting: temazepam

Medium

Short, medium, or long acting: alprazolam

Medium

Short, medium, or long acting: Clorazepate

Long

Short, medium, or long acting: Diazepam

Long

Short, medium, or long acting: Chlordiazepoxide

Long

Short, medium, or long acting: flurazepam

Long

First aid drugs test 3 Flashcards

(71 cards)