Antibitoics Flashcards Preview

Topnotch Pharmacology (Sept 2017) > Antibitoics > Flashcards

Flashcards in Antibitoics Deck (21):
1

May cause red man syndrome

Vancomycin

2

Peptide antibiotic that interferes with a late stage in cell wall synthesis in gram positive organism

Bacitracin

3

Antimetabolite, blocks incorporation of D ala into pentapeptise side chain of peptidoglycan

Cycloserine

4

May cause aplastic anemia and gray baby syndrome

Chloramphenicol

5

DOC for rickettsiae

Tetracycline

6

May cause tooth enamel dysplasia/discoloration

Tetracycline

7

Tetracycline should not be taken with

Milk

8

Only macrolide that does not inhibit CYP450

Azithromycin

9

Cross resistance b/n clindamycin and wc drug is commkn

Macrolide

10

Binds to 50s subunit. BACTERICIDAL

Quinupristin- dalfopristin

11

Basis for once daily aminoglycoside dosing

Post antibiotic effect

12

Has narrowest therapeutic window among aminoglycosides

Amikacin

13

Aminoglycoside used for endocarditis

Gentamicin

14

Aminoglycoside used for multi drug resistant TB

Amikacin

15

SE is nephrotoxicitu, ototoxicity and NM blockade

Aminoglycoside

16

Aminoglycoside used for brucellosis, tularemia, brucellosis

Streptomycin

17

Aminoglycoside that may cause congenital deafness

Streptomycin

18

Aminoglycoside used for skin infections, bowel prep for elective surgery, Hepatic enceph

Neomycin

19

Neomycin induced NM blockade may be reverse by

Calcium gluconate and neostigmine

20

Aminoglycoside used for drug resistant gonorrhea

Spectinomycin

21

Inhibits bacterial cell wall synthesis by binding to D Ala D ala terminus of nascent peptidoglycan

Vancomycin