Pancreatic Drugs Flashcards Preview

Topnotch Pharmacology (Sept 2017) > Pancreatic Drugs > Flashcards

Flashcards in Pancreatic Drugs Deck (31):
1

Somogyi

When evening dose of insulin is high

2

When evening dose of intermediate insulin is low

Waning

3

Phenomenon due to growth hormone spike

Dawm phenomenon

4

Most physiologic strategy for insulin therapy

Basal bolus

5

1st gen sulfonylurea

Chlorpropamide

6

May cause disulfiram rxn

Chlorpropamide

7

2nd gen sulfonylurea

Glipizide

8

CI in patients with hepatic impairment and renal insufficiency

Glipizide (2nd gen)

9

A meglitinide

Repaglinide

10

Increases insulin secretion from pancreatic B cells by closing ATP sensitive K channels

Secretagogued

11

Activates AMP stimulated and protein kinase leading to inhibition of hepatic and renal gluceneogenesis

Biguanides

12

Increase target tissue sensitvity to insulin by activating the peroxisome proliferator activated receptor gama nuclear receptor

Thiazolidinediones

13

Inhibit a glucosidase enzyme

Alpha glucosidase inhibitors

14

Example of aloha glucosidase inhibitor

Acarbose

15

Amylin analog

Pramlintide

16

Incretin modulator

Exanatide

17

DPP4 inhibitor

Sitagliptin

18

Inhibits GI and pancreatic lipases; reduces absorption of fats

Orlistat

19

Inhibits NE and Serotonin reuptake in the cns

Sibutramine

20

Selectively blocks cannabinoid(CB 1 receptors

Rimonabant

21

Anti obestiy drug with SE of suicidality

Rimonabant

22

For severe hypoglycemia and beta blocker overdose

Glucagon

23

Recombinant parathyroid hormone

Teriparatide

24

Active vitamin d

Calcitrol

25

Used for secondary hyperparathyroidism in CKD

Calcitrol

26

Inhibits bone resorption therefore decreasing serum calcium and phosphate

Calcitonin

27

Used for paget disease

Calcitonin

28

Supresses activity of osteoclasts. Inhibits bone resoprtion

Alendronate

29

Example of bisphosphonate

Alendroanate

30

A phosphate binding resin

Sevelamer

31

May mask signs of hypoglycemia

Beta blockers