Pancreatic Drugs

Question 1

Somogyi

Answer 1

When evening dose of insulin is high

Question 2

When evening dose of intermediate insulin is low

Answer 2

Waning

Question 3

Phenomenon due to growth hormone spike

Answer 3

Dawm phenomenon

Question 4

Most physiologic strategy for insulin therapy

Answer 4

Basal bolus

Question 5

1st gen sulfonylurea

Answer 5

Chlorpropamide

Question 6

May cause disulfiram rxn

Answer 6

Chlorpropamide

Question 7

2nd gen sulfonylurea

Answer 7

Glipizide

Question 8

CI in patients with hepatic impairment and renal insufficiency

Answer 8

Glipizide (2nd gen)

Question 9

A meglitinide

Answer 9

Repaglinide

Question 10

Increases insulin secretion from pancreatic B cells by closing ATP sensitive K channels

Answer 10

Secretagogued

Question 11

Activates AMP stimulated and protein kinase leading to inhibition of hepatic and renal gluceneogenesis

Answer 11

Biguanides

Question 12

Increase target tissue sensitvity to insulin by activating the peroxisome proliferator activated receptor gama nuclear receptor

Answer 12

Thiazolidinediones

Question 13

Inhibit a glucosidase enzyme

Answer 13

Alpha glucosidase inhibitors

Question 14

Example of aloha glucosidase inhibitor

Answer 14

Acarbose

Question 15

Amylin analog

Answer 15

Pramlintide

Question 16

Incretin modulator

Answer 16

Exanatide

Question 17

DPP4 inhibitor

Answer 17

Sitagliptin

Question 18

Inhibits GI and pancreatic lipases; reduces absorption of fats

Answer 18

Orlistat

Question 19

Inhibits NE and Serotonin reuptake in the cns

Answer 19

Sibutramine

Question 20

Selectively blocks cannabinoid(CB 1 receptors

Answer 20

Rimonabant

Question 21

Anti obestiy drug with SE of suicidality

Answer 21

Rimonabant

Question 22

For severe hypoglycemia and beta blocker overdose

Answer 22

Glucagon

Question 23

Recombinant parathyroid hormone

Answer 23

Teriparatide

Question 24

Active vitamin d

Answer 24

Calcitrol

Question 25

Used for secondary hyperparathyroidism in CKD

Answer 25

Calcitrol

Question 26

Inhibits bone resorption therefore decreasing serum calcium and phosphate

Answer 26

Calcitonin

Question 27

Used for paget disease

Answer 27

Calcitonin

Question 28

Supresses activity of osteoclasts. Inhibits bone resoprtion

Answer 28

Alendronate

Question 29

Example of bisphosphonate

Answer 29

Alendroanate

Question 30

A phosphate binding resin

Answer 30

Sevelamer

Question 31

May mask signs of hypoglycemia

Answer 31

Beta blockers