Antineoplastics 1 Flashcards Preview

Ther 201 3rd Exam > Antineoplastics 1 > Flashcards

Flashcards in Antineoplastics 1 Deck (39)
Loading flashcards...
30

Bone marrow depression but
Infrequent nausea and vomiting
No alopecia
No renal, hepatic deficits

Melphalan

31

Slowest acting nitrogen mustard, bone marrow depression with high doses, long perio

Chlorambucil

32

Nitrosurea, similar to bifunctional alkylating agents but with carbamoylating activity, high lipophilicity, crosses BBB

BCNU (carmustine)

33

Alkylsulfonate

Busulfan

34

Pulmonary infiltrates and fibrosis

Busulfan

35

Inorganic water soluble platinum containing complex

Cisplatin

36

Nausea and vomiting
Nephrotoxicity delayed, dose limiting
OTOTOXICITY
Mild to mod myelosuppression

Cisplatin

37

Alkylating agents

Mechlorethamine
Cyclophosphamide
Busulfan
Melphalan
Chlorambucil
BCNU (carmustine)
Cisplatin

38

Nitrogen mustard

Mechlorethamine
Melphalan
Chlorambucil