Antiparasitics 1 Flashcards Preview

Ther 201 3rd Exam > Antiparasitics 1 > Flashcards

Flashcards in Antiparasitics 1 Deck (45)
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30

Endoperoxide containing natural antimalarials from sweet wormwood

Artemisinin

31

Lumefantrine, when taken with food

Improved absorption

32

Minor arrhythmia and long qt

Coartem

33

Quinine effect adverse

Cinchonism
Git distress, headache, vertigo, blurred vision, tinnitus

34

Quinine moa

Complexes with dsDNA preventing separation

35

Therapeutic dose may cause hypoglycemia by insulin release, especially in severe infections in pregnant patients

Quinine

36

Not usually used unless sure that it is vivax

Chloroquine

37

Prevents biocrystallization of parasite heme into hemozoin causing heme buildup and parasite lysis

Chloroquine

38

Alopecia, hair bleaching, hypotension, widened qrs, abnormal t waves

Chloroquine

39

Antifolate drugs, malaria

Pyrimethamine
Sulfadoxime

40

Fansidar

Fixed combination
Sulfadoxime and
Pyrimethamine

41

May cause folic acid deficiency

Pyrimethamine

42

Eradicates exoerythrocytic and gametocytic forms

Primaquine

43

With longer tissue stage, falciparum or vivax?

Vivax

44

How many days of primaquine?

Falciparum 1
Vivax 14