Flashcards in Antiparasitics 1 Deck (45)
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30
Endoperoxide containing natural antimalarials from sweet wormwood
Artemisinin
31
Lumefantrine, when taken with food
Improved absorption
32
Minor arrhythmia and long qt
Coartem
33
Quinine effect adverse
Cinchonism
Git distress, headache, vertigo, blurred vision, tinnitus
34
Quinine moa
Complexes with dsDNA preventing separation
35
Therapeutic dose may cause hypoglycemia by insulin release, especially in severe infections in pregnant patients
Quinine
36
Not usually used unless sure that it is vivax
Chloroquine
37
Prevents biocrystallization of parasite heme into hemozoin causing heme buildup and parasite lysis
Chloroquine
38
Alopecia, hair bleaching, hypotension, widened qrs, abnormal t waves
Chloroquine
39
Antifolate drugs, malaria
Pyrimethamine
Sulfadoxime
40
Fansidar
Fixed combination
Sulfadoxime and
Pyrimethamine
41
May cause folic acid deficiency
Pyrimethamine
42
Eradicates exoerythrocytic and gametocytic forms
Primaquine
43
With longer tissue stage, falciparum or vivax?
Vivax
44
