Flashcards in CCDM: TOPIC SMALLPOX Deck (10)
The last naturally acquired case of smallpox in the world occurred in what year and country?
Oct 1977 in Somalia
When was global eradication certified and by what group?
1979 by WHO and sanctioned by World Health Assembly (WHA) in May 1980.
Where are all known variola virus stocks held under security?
CDC, Atlanta GA, USA and the Russian Federation Novosibirsk Region.
Smallpox signs and symptoms are?
high fever (40°C/104°F), malaise, headache, prostration, severe backache and occasional abdominal pain and vomiting
What are two types of smallpox?
variola minor (alastrim) and variola major
What is variola minor case fatality rate?
less than 1%
What is variola major case fatality rate?
Among unvaccinated populations of 20-50% or more with death occurring on fifth and seventh day.
Infectious agent of Smallpox
Variola virus, a species of Orthopoxvirus
Mode of transmission for Smallpox
Respiratory tract (droplet spread) or skin inoculation