Chlamydia & Chlamydophila Flashcards Preview

Microbiology Block 3 > Chlamydia & Chlamydophila > Flashcards

Flashcards in Chlamydia & Chlamydophila Deck (48)
Loading flashcards...
1

biology?

  • Obligate intracellular pathogen (OIP)*
  • Does NOT gram stain*
  • Do not make their own ATP
  • Infect mucous membranes*
  • causes Cytoplasmic “inclusion” bodies*

2

what are the 2 forms of chlamydia?

EB = Elementary body*

RB = Reticulate body*

 

3

elementary body is found in what stage?

where is it found?

Infectious stage* – attaches to host cell – internalized

4

does the elementary body replicate?

Non-replicating

5

the elementary body will transform into what?

Transform into Reticular body within host cell

6

where is the Reticulate body* found?

does it replicate?

into what will it transform?

  • Found inside cytoplasmic vacuole of host cell
  • it replicates
  • elementary body

7

what is this?

chlamydia, cytoplasmic inclusion body

8

what cytologic stain can be used to view chlamydia?

what other technique can be used for chlamydia?

pap smear *

Immunofluorescent stains (better) *

9

what is this?

what technique?

chlamydia

pap smear

10

what technique is this?

Immunofluorescent stain*

11

what are the medically important chlamydia and chlamydophila?

Chlamydia trachomatis

Chlamydophila pneumoniae

Chlamydophila psittaci

12

what are the different chlamydia trachomatis and what will they cause?

A, B, Ba, C = Trachoma (blinding ocular disease)

D - K = Urogenital infections (STD)

L1,   L2,   L3 = Lymphogranuloma venereum

13

what will be found inside host cells, metabolically active and replicating with chlamydia trachomatis?

Reticulate bodies *

14

what is the inactive, extracellular infective form of chlamydia trachomatis?

elementary bodies *

15

what stain can be used to view chalmydia trachomatis?

Not seen on gram stain*

 

16

what is the Reservoir for chlamydia trachomatis?

Human genital tract and eyes *

 

17

Transmission of chlamydia trachomatis?

Sexual contact and during birth

Trachoma transmitted by - hand to eye contact and flies

18

what cells will chlamydia trachomatis infect?

Infects non-ciliated columnar or cuboidal epithelial cells of mucosal surfaces *

 

19

chlamydia trachomatis is the most common cause of what in the US?

Most common bacterial cause of STD in USA *

20

is it always symptomatic?

no, can be asymptomatic 

21

what can chlamydia trachomatis cause in males?

Nonspecific urethritis (non-gonococcal urethritis) *

 

22

what symptoms will men present with, in an infection with chlamydia trachomatis?

- Dysuria (painful urination) and

- Thin watery discharge containing 

- Numerous neutrophils but NO bacteria (on Gram staining) * = sterile pyuria *

23

what symptoms will women present with?

Urethritis and cervicitis *

Pelvic inflammatory disease (PID) *

 

24

Urethritis and cervicitis* in pregnant women infected with chlamydia can lead newborns to what?

conjunctivitis / atypical pneumonia in newborns *

 

25

how does pelvic inflammatory disease in women look like?

there is potential for scarring in what part of the female structures? which can lead to what?

  • Sexually transmitted ascending infection of female genital tract
  • mucopurulent discharge
  • Potential for fallopian tube scarring and for ectopic pregnancy* as a result

26

what complications can occur with chlamydia?

triad of:

- Conjunctivitis (noninfectious)  

- Urethritis (due to Chlamydia trachomatis)

- Reactive Arthritis (seronegative)

and 1 of these:

1) Achilles tendinitis 

2) Mucocutaneous lesions

27

what complications can occur in newborns?

Neonatal Conjunctivitis* (ophthalmia neonatorum)

Infant Atypical pneumonia * (interstitial pneumonia)

28

neonatal conjunctivitis is Characterized by what?

how is it treated?

mucopurulent discharge

Antibiotic eyedrops

29

Interstitial pneumonia in newborns is characterized by what?

- rhinitis followed by bronchitis

- characteristic dry cough (Staccato cough- very short and sharp).

30

what does chlamydia serotype L1, L2, L3 cause?

Lymphogranuloma venereum (LGV)