Cholinergic-Blocking Drugs Flashcards Preview

NCLEX > Cholinergic-Blocking Drugs > Flashcards

Flashcards in Cholinergic-Blocking Drugs Deck (15):
0

Atropine
(Functional Classification)

Antidysrhythmic, Anticholinergic Parasympatholytic, Antimuscarinic

1

Atropine
(Chemical Classification)

Belladonna Alkaloid

2

Atropine
(Mechanism of Action)

Blocks acetylcholine at parasympathetic neuroeffector sites; increases cardiac output, heart rate by blocking vagal stimulation in heart; dries secretion by blocking vagus

3

Atropine
(Uses)

Bradycardia <40-50bpm, bradydysrhythmia, reversal of anticholinesterase agents, insecticide poisoning, blocking cardiac vagal reflexes, decreasing secretions before surgery, antispasmodic with GU, biliary surgery, bronchodilator, AV heart block

4

Atropine
(Contraindications)

Hypersensitivity to belladonna alkaloids, closed-angle glaucoma, GI obstructions, myasthenia gravis, thyrotoxicosis, ulcerative colitis, prostatic hypertrophy, tachycardia/tachydysrhythmias, asthma, acute hemorrhage, severe hepatic disease, myocardial ischemia, paralytic ileus

5

Atropine
(Side Effects)

CNS: headache, dizziness, involuntary movement, confusion, psychosis, anxiety, COMA, flushing, drowsiness, insomnia, weakness; delirium (geriatric patients)
CV: hypo/hypertension, paradoxical bradycardia, angina, PVCs, TACHYCARDIA, ectopic ventricular beats
EENT: blurred vision, photophobia, glaucoma, eye pain, pupil, dilation, nasal congestion
GI: dry mouth, nausea, vomiting, abdominal pain, anorexia, constipation, PARALYTIC ILEUS, abdominal distention, altered taste
GU: retention, hesitancy, impotence, dysuria
INTEG: rash, urticaria, contact dermatitis, dry skin, flushing
MISC: suppression of lactation, decreased sweating

6

Atropine
(Nursing Considerations)

ASSESS:
-I&O ratio; check for urinary retention, daily output
-ECG for ectopic ventricular beats, PVC, tachycardia in cardiac patients
-For bowel sounds, constipation
-Respiratory status: rate, rhythm, cyanosis, wheezing, dyspnea, engorge neck veins
-INCREASED INTRAOCULAR PRESSURE: eye pain, nausea, vomiting, blurred vision, increased tearing
-Cardiac rate: rhythm, character, BP continuously
-Allergic reaction: rash, urticaria

PERFORM/PROVIDE:
-Sugarless hard candy, gum, frequent rinsing of mouth dryness

7

Atropine
(Overdose Treatment)

O2, artificial ventilation, ECG; administer DOPamine for circulatory depression; administer diazepam or thiopental for seizures; assess need for antidysrhythmics

8

Tolterodine (Detrol)
(Functional Classification)

Overactive bladder product

9

Tolterodine (Detrol)
(Chemical Classification)

Muscarinic receptor antagonist

10

Tolterodine (Detrol)
(Mechanism of Action)

Relaxes smooth muscles in urinary tract by inhibiting acetylcholine at postganglionic sites

11

Tolterodine (Detrol)
(Uses)

Overactive bladder (urinary frequency, urgency), urinary incontinence

12

Tolterodine (Detrol)
(Contraindications)

hypersensitivity, uncontrolled closed-angle glaucoma, urinary retention, gastric retention

13

Tolterodine (Detrol)
(Side Effects)

CNS: anxiety, paresthesia, fatigue, Dizziness, Headache; increasing dementia, memory impairment
CV: chest pain, hypertension, QT PROLONGATION
EENT: vision abnormalities, xerophthalmia
GI: Nausea, Vomiting, Anorexia, abdominal pain, constipation, dry mouth, dyspepsia
GU: dysuria, urinary retention, frequency, UTI
INTEG: rash, pruritus
RESP: bronchitis, cough, pharyngitis, upper respiratory tract infection
SYST: ANGIOEDEMA, STEVENS-JOHNSON SYNDROME

14

Tolterodine (Detrol)
(Nursing Considerations)

ASSESS:
-URINARY PATTERNS: distention, nocturia, frequency, urgency, incontinence
-SERIOUS SKIN DISORDERS: angioedema, Steven-Johnson syndrome; allergic reactions: rash; if this occurs, product should be discontinued
-LFTs at baseline, periodically
-QT PROLONGATION: ECG, ejection fraction; assess for chest pain, palpitations, dyspnea