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Flashcards in Respiratory Drugs Deck (21):
0

Albuterol
(Functional Classification)

Adrenergic Beta2-agonist, sympathomimetic bronchodilator

1

Albuterol
(Mechanism of Action)

Causes bronchodilation by action on beta2 (pulmonary) receptors by increasing levels of cAMP, which relaxes smooth muscle; produces bronchodilation, CNS, cardiac stimulation as well as increased diuresis and gastric acid secretion; longer acting than isoproterenol

2

Albuterol
(Uses)

Prevention of exercise-induced asthma, acute bronchospasm, bronchitis, emphysema, bronchiectasis, or other reversible airway obstruction

3

Albuterol
(Contraindications)

Hypersensitivity to sympathomimetics, tachydysrhythmias, severe cardiac disease, heart block

4

Albuterol
(Side Effect)

CNS: Tremors, Anxiety, insomnia, headache, dizziness, stimulation, Restlessness, hallucinations, flushing, irritability
CV: palpitations, tachycardia, angina, hypo/hypertension, dysrhythmias
EENT: dry nose, irritation of nose and throat
GI: heartburn, nausea, vomiting
MISC: flushing, sweating, anorexia, bad taste/ smell changes, hypokalemia
MS: muscle cramps
RESP: cough, wheezing, dyspnea, PARADOXICAL BRONCHOSPASM, dry throat

5

Albuterol
(Nursing Considerations)

ASSESS:
-Respiratory function: vital capacity, forced expiratory volume, ABGs; lung sounds, heart rate and rhythm, BP, sputum (baseline and peak); whether patient has not received theophylline therapy before giving dose
-Patient's ability to self-medicate
-For evidence of allergic reactions
-For paradoxical bronchospasm; hold medication, notify prescriber if bronchospasm occurs

6

Albuterol
(Overdose Treatment)

Administer Beta1-adrenergic blocker, IV fluids

7

Montelukast (Singulair)
(Functional Classification)

Bronchodilator

8

Montelukast (Singulair)
(Chemical Classification)

Leukotriene receptor antagonist, cysteinyl

9

Montelukast (Singulair)
(Mechanism of Action)

Inhibits leukotriene (LTD4) formation; leukotrienes exert their effects by increasing neutrophil, eosinophil migraine; aggregation of neutrophils, monocytes; smooth muscle contraction, capillary permeability; these actions further lead to bronchoconstriction, inflammation, edema

10

Montelukast (Singulair)
(Uses)

Chronic asthma in adults and children, seasonal allergic rhinitis, bronchospasm prophylaxis

11

Montelukast (Singulair)
(Contraindications)

Hypersensitivity

12

Montelukast (Singulair)
(Side Effects)

Dizziness, Fatigue, Headache, behavior, changes, SUICIDAL IDEATION, SUICIDE, hallucinations, SEIZURES, agitation, anxiety, depression, fever, drowsiness
GI: Abdominal Pain, dyspepsia, nausea, vomiting, diarrhea, PANCREATITIS
HEMA: THROMBOCYTOPENIA
INTEG: rash, pruritus, erythema
MS: asthenia, myalgia, muscle cramps
RESP: Influenza, Cough, nasal congestion
SYST: ANAPHYLAXIS, ANGIOEDEMA, CHURG-STRAUSS SYNDROME

13

Montelukast (Singulair)
(Nursing Considerations)

ASSESS:
-CHURG-STRAUSS SYNDROME: adult patients carefully for symptoms: eosinophilia, vasculitic rash, worsening pulmonary symptoms, cardiac complications, neuropathy
-CBC, blood chemistry during treatment
-Respiratory rate, rhythm, depth; auscultate lung field bilaterally; notify prescriber of abnormalities
-Allergic reactions: rash, urticaria; product should be discontinued
-For behavior changes and suicidal ideation, other neuropsychiatric reactions

14

Salmeterol (Serevent)
(Functional Classification)

Beta2-Adrenergic agonist, bronchodilator

15

Salmeterol (Serevent)
(Mechanism of Action)

Causes bronchodilation by action on beta2 (pulmonary) receptors by increasing levels of cAMP, which relaxes smooth muscle with very little effect on heart rate; maintains improvement in FEV from 3 to 12hr; prevents nocturnal asthma symptoms

16

Salmeterol (Serevent)
(Uses)

Prevention of exercise-induced bronchospasm, COPD, asthma

17

Salmeterol (Serevent)
(Contraindications)

Hypersensitivity to sympathomimetics, tachydysrhythmias, severe cardiac disease, monotherapy treatment of asthma

18

Salmeterol (Serevent)
(Side Effects)

CNS: Tremors, Anxiety, insomnia, headache, dizziness, fever
CV: palpitations, tachycardia, hypo/hypertension, angina, dysrhythmias
EENT: dry nose, irritation of nose and throat
GI: heartburn, nausea, vomiting, abdominal pain
MS: muscle cramps
RESP: BRONCHOSPASM, cough

19

Salmeterol (Serevent)
(Nursing Considerations)

ASSESS:
-RESPIRATORY FUNCTION: vital capacity, forced expiratory volume, ABGs, lung sounds, heart rate and rhythm
-PARADOXICAL BRONCHOSPASM: dyspnea, wheezing, chest tightness

20

Salmeterol (Serevent)
(Overdose Treatment)

Beta2-Adrenergic blocker