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Flashcards in CNS Infections Deck (14):
1

What are 4 dental related CNS infections?

1-Abscess
2-Empyema
3-Meningitis
4-Encephalomyelitis

2

What are the 2 main ways to cause CNS infection from oral illness?

1-Direct extension of acute oral infections (Caries/pulpitis, Periodontitis, Abscess, NUG)
2-Bacteremia

3

Which CNS condition is the most common infection from secondary dental pathology, results in changes in consciousness, focal neurologic signs, vomiting and fever?

CNS abscess

*Oral pathology, procedures, immunocompromise, heart disease, skull fx, meningitis, sinus infection; all risk factors

4

The liquefactive nature of a bacterial abscess in the brain is treated in what two ways?

1-Antibiotics
2-Surgery (>2.5cm)

5

What organism is a branching filamentous bacteria that is gram positive, non-acid fast, is normal oral flora and aerobic/microaerophilic?

Actinomyces

6

Which organism family is the most common neurosurgical organism in immunocompromised patients?

Mycoses

*Aspergillus, Zygomycetes, Candida, Crytococcus neoformans, dimorphic fungi

7

What organism is the most common pathogen of brain infection, presents with focal symptoms, and is treated by aggressive surgical excision as well as amphotericin B + flu cytosine?

Aspergillus

*Can be single/multiple abscess, granulomata, infarcted brain

8

Which organism presents as rapid facial swelling, is wide and ribbon like with 90 degree branching and is a risk factor is diabetics and immunosuppressed patients?

Zygomycetes

*Mucor, Rhizomucor, Rhizopus

9

Which organism rarely causes CNS infection, is treated through multimodal antifungals and can cause meningitis, encephalitis or abscess?

Candida

10

What are 4 CNS infections not orally related?

1-Parasites
2-Spirochetes
3-Viruses
4-Prion disease

11

What two parasitoses are caused by helminths and protozoa respectively?

Helminth- Neurocystercercosis (taenia solum)
Protozoa- Toxoplasmosis (toxoplasma gondii)

12

What non-dental organism causes neurosyphilis (treponema palladium) lyme disease (barrel burgdorferi) and are uncommon neurosurgical specimens?

Spirochetes

13

What are the two main issues causes by Herpes virus?

1-Herpetic gingivostomatitis (very common)
2-Herpes simplex encephaliits (rare)

14

Which group of organisms are slow viruses thatcause abnormal protein folding such as in Creutzfeldt-Jakob disease?

Prions