Day 10 - HemOnc2 Quiz Flashcards Preview

Step 2 DIT Rapid Review > Day 10 - HemOnc2 Quiz > Flashcards

Flashcards in Day 10 - HemOnc2 Quiz Deck (21):
1

TTP Pentad

Thrombocytopenia, hemolytic anemia, renal failure => uremia (HUS); fever, neuro sx (AMS, seizures, coma)

2

Most common mutation in white pts predisposing to venous thrombosis

Factor V leiden

3

Drug mechanism: Streptokinase

thrombolytic (like tPA), cleaves fibrin clots

4

Drug mechanism: ASA

Inhibits cyclooxygenase, inhibiting platelet aggregation

5

Drug mechanism: Clopidogrel

ADP receptor blocker

6

Drug mechanism: Abciximab

GpIIbIIIa inhibitor (like Tirofaban)

7

Drug mechanism: Ticlopidine

ADP receptor blocker (like clopidogrel)

8

Drug mechanism: Enoxaparin

LMWH, inhibits factor Xa

9

Drug mechanism: Eptefibitide

GIIbIIIa inhibitor

10

Lab test(s) used to monitor: (1) warfarin (2) heparin (3) LMWH

(1) INR (2) PTT (3) Anti-Factor Xa (if needed to be monitored)

11

Tx vWD

Desmopressin; Severe bleeding - cryoprecipitate or Factor VIII; Menorrhagia - OCPs; Avoid ASA and other platelet inhibitors

12

Lab changes: HUS/TTP

Low platelet count, Elevated bleeding time, Normal PT/PTT

13

Lab changes: Hemophilia A/B

Elevated PTT, Normal PT, platelet count and bleeding time

14

Lab changes: vWD

Normal platelet count, Elevated bleeding time, Normal PT, Elevated PTT

15

Lab changes: DIC

Platelet count low, Bleeding time high, PT/PTT Elevated

16

Lab changes: Warfarin use

Normal platelet count and bleeding time, Elevated PT/PTT

17

Lab changes: End-stage liver disease

Low/Normal platelet count and correlated High/Normal bleeding time; Elevated PT/PTT

18

Lab changes: ASA use

Normal platelet count, Increased bleeding time; Normal PT/PTT

19

Criteria for SIRS

2 of 4 following criteria: (1) Fever or Hypothermia (2) Tachypnea (> 20) (3) Tachycardia (>90) (4) Leukopenia (12K)/Bandemia (>10%)

20

Most important med in anaphylaxis

Epinephrine

21

Most common causes of DIC

"STOP Making New Thrombi": Sepsis, Trauma (including extensive surgery), Obstetric complications, Pancreatitis (acute), Malignancy, (Nephrotic syndrome?), Transfusion reactions

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