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Flashcards in Day 10 - HemOnc1 Deck (2):

Characteristic findings of hereditary spherocytosis

Elevated bilirubin: jaundice, gallstones (all hemolytic anemias); Splenomegaly, Anemia w/ reticulocytosis, Increased MCHC; Higher incidence of pseudohyperkalemia; Smear shows spherocytes; Dx w/ positive osmotic fragility test


Tx hereditary spherocytosis

Folic acid daily; RBC transfusion if severe anemia; Splenectomy in moderate to severe cases

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