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Flashcards in Drugs Neuro Deck (125)
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1
Q

Gabapentin

A

antiepileptic

2
Q

Pregablin

A

antiepileptic

3
Q

Tiagabine

A

antiepileptic

Inhibits GABA reuptake

4
Q

Volparate

A

Antiepileptic

5
Q

Propanalol

A

Betaadrenoceptor

6
Q

Citalopram

A

SSRI

7
Q

Venlafaxine

A

SSRI

8
Q

Zolpidem

A

Benzo

9
Q

Triazolam

A

Benoz

10
Q

Loprazolam

A

Benoz

11
Q

Nitrazepam

A

Benzo

12
Q

Diazepam

A

Benzo

13
Q

Phenobarbitone

A

Barbituates (GABAa receptor enhancement) used as anxiolytic and anticonvulsant

14
Q

Busipirone

A

5-HT1a agonist - anxiolytic

15
Q

Ipsapirone

A

5-HT1a agonist - anxiolytic

16
Q

Gepirone

A

5-HT1a agonist - anxiolytic

17
Q

Olanzapine

A

Antipsychotics

18
Q

Risperidone

A

Antipychotic

19
Q

Zopiclone

A

Hypnotic

20
Q

Zolpidem

A

Hypnotic

21
Q

Chloral hydrate

A

Hypnotic

22
Q

Diphenhydramine

A

antihistamine

23
Q

Promethazine

A

Antihistamine

24
Q

Mepivacaine

A

LA

25
Q

Bupivacaine

A

LA -> epidural

26
Q

Prilocaine

A

LA intravenous e.g limb surgery

27
Q

Tetracaine

A

Surface anesthesia LA cornea

28
Q

Articaine

A

LA

29
Q

Lignocaine

A

Surface anesthesia or intravenous or epidural e.g. limbs surgery

30
Q

Thipentaie

A

Injection/intravenous Anesthetic

31
Q

Propofol

A

Injection/intravenous Anesthetic

32
Q

Etomidate

A

Injection/intravenous Anesthetic

33
Q

Midazolam

A

Benzo (used as GA)

Injection/intravenous Anesthetic

34
Q

Ketamine

A

NMDA channel blocker

Injection/intravenous Anesthetic

35
Q

Nitrous Oxide

A

Inhalation anesthetics

36
Q

Isoflurane

A

Inhalation anesthetics

37
Q

Desflurane

A

Inhalation anesthetics

38
Q

Sevoflurane

A

Inhalation anesthetics

39
Q

Atropine

A

Muscarinic antagonists

40
Q

Atracurium

A

NMJ blovking agent (GA use)

41
Q

Tiletamine

A

Dissociative anaesthetic

42
Q

Morphine

A

opioid

43
Q

Heroin

A

opioid

44
Q

Codeine

A

opioid

45
Q

Oxycodone

A

Opioid

46
Q

Methadone

A

Opioid

47
Q

Pethidine

A

opioid will cross placenta

48
Q

Pentazocaine

A

Opioid

49
Q

Fentanyl

A

Opioid

50
Q

Remifentanyl

A

Opioid

51
Q

Buprenorphine

A

Opioid

52
Q

Tramadol

A

opioid/ Noradrenaline re-uptake inhibitor

53
Q

Nalozone

A

Opioid receptor antagonist to prevent abuse

54
Q

Naltrexone

A

Opioid receptor antagonist to prevent abuse

55
Q

Dextromethorphan

A

Cough suppressant (non-opioid)

56
Q

Co-codamol

A

codeine and paracetamol

57
Q

Co-codraprin

A

Codeine and aspirin

58
Q

Co-proxamol

A

dextropropoxyphene + paracetamol

59
Q

Carbamazepine use

A

Trigeminal neuralgia

Na channel blocker (anticonvulsant)

60
Q

Gabapentin/pregablin use

A

Diabetic neuropathy

61
Q

Amtitriptyline

A

Antidepressant used in post herpatic neuralgia

62
Q

Sodium valporate

A

Anticonvulsant
1. potentiate GABA actions at GABAa R

  1. Inhibits GABA transaminase
  2. Inhibitis SSA dehydrogenase
  3. blocks voltage-gated sodium channels
63
Q

Felbamate

A
  1. Potentiate GABA actions at GABAa R (anticonvulsant)

2. NMDA antagonist anticonvulsant

64
Q

Perampenal

A

AMPA antagonists (anticonvulsant)

65
Q

Carbamaxepine

A

blocks voltage-gated sodium channels

Anticonvulsant action

66
Q

Oxcarbazepine

A

blocks voltage-gated sodium channels

Anticonvulsant action

67
Q

Phenytoin

A
  1. blocks voltage-gated sodium channels
  2. Block of voltage-activated calcium channels
    Anticonvulsant action
68
Q

Lamotrigine

A
  1. blocks voltage-gated sodium channels
  2. Block of voltage-activated calcium channels
    Anticonvulsant action
69
Q

Ethosuximde

A

Block of voltage-activated calcium channels (low voltage)

70
Q

Gabapentin

A

Specifically blocks transport of voltage-gated calcium channels to the membrane

71
Q

Topiramate

A
Treatment of migraine along with anticonvulsant
Multpiple actions (GABA, block sodium and calcium, Blocks AMPA)
72
Q

Levetiracetum

A

anticonvulsant

73
Q

Zonisamide

A

Na channel block - anticonvulsant

74
Q

Retigabine

A

Activates KCNQ potassium channels

75
Q

Busipirone

A

Post-synaptic receptor agonist of monoamines

76
Q

Mirazepine

A

Pre-synaptic receptor antgonists for monoamine

Anti-D

77
Q

Moclobemide

A

MAOIs

Anti-D

78
Q

Phenylzine

A

MAOIs

Anti-D

79
Q

Fluoextine

A

SSRI

Anti-D

80
Q

Iproniazid

A

MAOI

Anti-D

81
Q

Imipramine

A

TCA

Anti-D

82
Q

Amitriptyline

A

TCA

Anti-D

83
Q

Clomipramine

A

TCA

Anti-D

84
Q

Despiramine

A

TCA

Anti-D

85
Q

Paroxetine

A

SSRI

Anti-D

86
Q

Reboxetine

A

Selective Noradrenaline reuptake inhibitor

Anti-D

87
Q

Trazadone

A

5-HT2 antagonists + SSRI

Anti-D (atypical)

88
Q

Nefazedone

A

5-HT2 antagonist +SNRI/SSRI

Anti-D (atypical)

89
Q

Mianserin

A

Alpha-adrenoceptor and 5-HT and 5-HT antagonist

Anti-D (atypical)

90
Q

Mirtazepine

A

Alpha-adrenoceptor and 5-HT and 5-HT antagonist

Anti-D (atypical)

91
Q

Lithium

A

mood stabiliser

92
Q

Fuoxetine

A

SSRI

93
Q

Agonelatine

A

Melatonin agonists and 5-HT2 antagonist

94
Q

Phenothiazines

A

Primary D2-receptor antagonists

Typical anti-pyschotics

95
Q

Chlorpromazine

A

Primary D2-receptor antagonists

Typical anti-pyschotics

96
Q

Fluphenazine

A

Primary D2-receptor antagonists

Typical anti-pyschotics

97
Q

Thioridazines

A

Primary D2-receptor antagonists

Typical anti-pyschotics

98
Q

Butyrophenones

A

Primary D2-receptor antagonists

Typical anti-pyschotics

99
Q

Haloperidol

A

Primary D2-receptor antagonists

Typical anti-pyschotics

100
Q

Pimozide

A

Primary D2-receptor antagonists

Typical anti-pyschotics

101
Q

Clozapine

A

Also know as Serotonin (5-HT2) and dopamine (D2) antagonists

Atypical antipyschotics

102
Q

Risperidone

A

Also know as Serotonin (5-HT2) and dopamine (D2) antagonists

Atypical antipyschotics

103
Q

Quetoapine

A

Also know as Serotonin (5-HT2) and dopamine (D2) antagonists

Atypical antipyschotics

104
Q

Zotepine

A

Also know as Serotonin (5-HT2) and dopamine (D2) antagonists

Atypical antipyschotics

105
Q

Aripriprazole

A

Also know as Serotonin (5-HT2) and dopamine (D2) antagonists

Atypical antipyschotics

106
Q

Sertaline

A

SSRI

107
Q

Rupropion

A

MOAI (DA) smoking cessation

108
Q

Methylphenodate

A

Ritalin

ADHD

109
Q

Atomoxetine

A

MOAI (NA)

110
Q

Modafinil

A

Cognitiveenhancers

111
Q

Fenfluramine

A

SSRI

112
Q

Sibutramine

A

NA/5-HT re-uptake inhibitorq

113
Q

Romonabant

A

Selective CB1 receptor blocker

114
Q

Lorcaserin →

A

Selective 5-HT2c receptor agonist

115
Q

Orlistata

A

Lipase inhibitor which prevents fat breakdown and absorption.

116
Q

a. Levodopa (L-Dopa)

A

dopamine agonist

117
Q

Prampipexole (Mirapexin)

A

Direct Dopamine Receptor Agonists:

118
Q

Ropinirole (eg Adartel, Requip)

A

Direct Dopamine Receptor Agonists:

119
Q

Rotigotine (Neupro)

A

Direct Dopamine Receptor Agonists:

120
Q

Selegiline

A

Inhibitors of dopamine metabolism:

Irreversible MAO-B inhibitor

121
Q

Rasagiline

A

Inhibitors of dopamine metabolism:

122
Q

Entacapone

A

Inhibitors of dopamine metabolism:

123
Q

Tolcapone

A

Inhibitors of dopamine metabolism:

124
Q

Amantidine:

A

Antiviral agent

Parkinsons

125
Q

Memantine:

A

NMDA receptor antagonist

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