Flashcards in Seminar G Polyarteritis Nodosa Deck (5)
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1
Definition
A rare systemic illness characterised by necrotising inflammation of medium-sized arteries leading to aneurysm formation.
Principally affects viscera, and may lead to organ infarction if left untreated
2
Clinical Features
Fever
Weight loss
Malaise
GI upset
Vasculitic rash
Renal, pulmonary and CVS involvement may also occur
Peripheral neuropathy may also occu, due to involvement of the vasa nervorum
3
Association with
HEP B infection
4
Clinical diagnosis may be confirmed either by
Histological analysis of affected organs
Coeliac axis or renal arteriograms (beading pattern of microaneurysms)
5
