EXAM #2: PANCREATITIS Flashcards Preview

Gastrointestinal System > EXAM #2: PANCREATITIS > Flashcards

Flashcards in EXAM #2: PANCREATITIS Deck (25):
1

What is the Sphincter of Oddi?

- Circular band of muscle at the bottom of the biliary tree
- Controls the flow of pancreatic juices and bile into 2nd part of duodenum

2

What neutralizes gastric acid as the meal enters the small intestine?

Bicarbonate

3

What turns a meal into liquid for absorption?

Digestive enzymes

4

What signals the body to store ingested nutrients?

Insulin

5

Why are patients with acute pancreatitis kept NPO for 48 hours after presentation?

Pancreatic rest
- Turn off the pancreas

When the patient eats again, some pain is normal and indicates that the pancreas is turned back on.

6

What pancreatic endocrine cells secrete glucogon?

Alpha

7

What pancreatic endocrine cells secrete insulin?

Beta

8

What pancreatic endocrine cells secrete somatostatin?

Delta

9

What pancreatic exocrine cells produce bicarbonate?

Centroacinar

10

What pancreatic exocrine cells produce digestive enzymes?

Basophilic cells

11

What are the two primary etiologies of acute pancreatitis?

1) Alcohol
2) Gallstones

Choledocholithiasis= a gallstone that is stuck in the bile duct.

12

What is the classical manifestation of acute pancreatitis?

- Constant epigastric abdominal pain that radiates to the back
- Anorexia

13

What are the classic physical exam findings in acute pancreatitis?

- Appears in pain
- Tachycardia
- Epigastric tenderness with guarding

Note that you may see "Cullen's or Grey Turner's" signs i.e. periumbilical bleeding and flank bleeding

14

When should you image a patient with suspected acute pancreatitis?

1) New case (no prior history)
2) Atypical presentation

15

What imaging modalities should be used for imaging if there is suspected acute pancreatitis?

1) US
2) CT w/ IV contrast

16

What test do you need to order before giving IV contrast?

BMP and Creatinine

17

What labs should be ordered to work-up acute pancreatitis?

1) CBC*
2) BMP or CMP*
3) Lipase
4) Liver enzymes and bilirubin

*Few cases (in sim lab) where this isn't warranted

18

What are the synthetic liver function markers?

Albumin and PT/INR

19

How is acute pancreatitis treated?

1) NPO
2) Hydration--several boluses of IV fluid
3) Pain control
4) +/- antibiotics

20

What do you need to do after treating acute pancreatitis?

Address the underlying cause

21

How long does it take for the clinical resolution of acute pancreatitis?

3-7 days

22

What are the potential serious complications of acute pancreatitis?

1) Shock
2) ARDS
3) Renal failure
4) GI hemorrhage
5) DIC

23

What are the less severe complications of acute pancreatitis?

1) Metabolic abnormalities
- Hypocalcemia (Soponification)
- Hyperglycemia
- Hypertriglyceridemia
2) Pseudocyst formation
3) Pancreatic necrosis
4) Infection

24

What are the complications of chronic pancreatitis?

1) DM
2) Persistent abdominal pain
3) Chronic diarrhea
4) Malnourishment

25

What does a 2:1 ratio or greater of AST:ALT indicate?

Alcoholic liver disease