Infection - Pertussis Flashcards
(37 cards)
1
Q
Causative Organism of Pertussis
A
- Bordetella pertussis & Para-pertussis (Only in human)
2
Q
Characters of Bordetella pertussis
A
- Gram -ve coccobacilli
- Aerobic
- Grows on starch blood agar
3
Q
MOI by Pertussis
A
- Direct droplet “Highly contagious with 100% attack rate”
4
Q
IP by Pertussis
A
- 3 - 12 days “Up to 28 days”
5
Q
Infectivity Period for Pertussis
A
- No therapy: 5 weeks
- Therapy: 5 days
6
Q
Incidence of Pertussis
A
- 60 million cases of pertussis occur worldwide / year
- More than 500,000 deaths
7
Q
Age in Pertussis
A
- The peak incidence was in children 1 - 5 year after vaccine coverage
- Approximately 50% of cases occurs in infants < 1 year
- 25% in adolescents and adults
8
Q
Pathogensis of Pertussis
A
9
Q
CP of Pertussis
A
10
Q
CP of Pertussis
- Catarrhal Stage
A
- FAHM
- ANVC
- Rhinorrhea, lacrimation & conjunctival injection
11
Q
CP of Pertussis
- Paroxysmal Stage
A
12
Q
Paroxysmal Stage of Pertussis
- PPT by
A
- Sneezing
- Yawing
- Eating
13
Q
Paroxysmal Stage of Pertussis
- Associated with
A
14
Q
Paroxysmal Stage of Pertussis
- Followed By
A
- Loud whop (inspired air passes through partially closed airways)
- Post-tussive exhaustion (Major clue to diagnosis)
- Post-tussive emesis
15
Q
CP of Pertussis
- Convalesent Stage
A
- During this stage the number, severity and duration of episodes diminish.
16
Q
Pertussis in infant
- Catarrhal Stage
- Paroxysmal Stage
- Convalescent Stage
A
17
Q
Complications of Pertussis
A
18
Q
Complication of Pertussis
- Apnea
A
….
19
Q
Complication of Pertussis
- Secondary Bacterial Infections
A
- pneumonia and otitis media
20
Q
Complication of Pertussis
- Encephalopathy
A
- Apnea, intracranial hemorrhage or hypoxemia that may associate cough
21
Q
Complication of Pertussis
- Physical Sequale of forceful cough
A
22
Q
Dx of Pertussis
A
23
Q
Dx of Pertussis
- Clinically
A
24
Q
Dx of Pertussis
- Labs
A
25
Labs in **Pertussis**
- CBC
- Culture
- Serology
- Chest X-Ray
26
DDx of **Pertussis**
27
Prevention of **Pertussis**
28
Prevention of **Pertussis**
- Control
29
Prevention of **Pertussis**
- Prevention
- Whole or better acellular pertussis vaccine.
30
TTT of **Pertussis**
31
TTT of **Pertussis**
- Antimicrobials
32
TTT of **Pertussis**
- Salbutamol
May be of benefit
33
TTT of **Pertussis**
- Corticosteroids
- No evidence of beneficial effect
34
TTT of **Pertussis**
- Hospitalization
35
Hospitalization in TTT of **Pertussis**
- Indications
36
Hospitalization in TTT of **Pertussis**
- Goals
37
TTT of **Pertussis**
- Hospital Care
