L10: AIH & MLD

Question 1

Def of AIH

Answer 1

Question 2

Def of AIH

• 3 Yes

Answer 2

Question 3

Def of AIH

• 3 No

Answer 3

Question 4

Incidence of AIH

Answer 4

More in adolescent females

Question 5

Classification of AIH

Answer 5

Question 6

Compare Between Type I & Type II AIH

Answer 6

Question 7

Compare Between Type I & Type II AIH

• Anti-Bodies
• Incidence
• Age
• Severity
• Response to TTT

Answer 7

Question 8

CP of AIH

Answer 8

Question 9

CP of AIH

• Symptomatic Chronic HBV

Answer 9

Question 10

CP of AIH

• Extra-Hepatic Manifestations

Answer 10

Question 11

Pattern of Presentation AIH

Answer 11

Question 12

INVx for AIH

Answer 12

Question 13

INVx for AIH

• Scheme

Answer 13

Question 14

INVx for AIH

• Labs

Answer 14

Question 15

INVx for AIH

• Bx

Answer 15

Question 16

DDx of AIH

Answer 16

Question 17

TTT of AIH

Answer 17

Question 18

TTT of AIH

• Lines

Answer 18

Question 19

TTT of AIH

• Indications

Answer 19

Question 20

TTT of AIH

• When to stop?

Answer 20

Question 21

Examples of MLD

Question 22

Ex in Chronic Hepatitis D2 Alpha 1 Anti-Trypsin Deficiency

Answer 22

…….

Question 23

INVx for Chronic Hepatitis D2 Alpha 1 Anti-Trypsin Deficiency

Answer 23

1. a1 anti-trypsin phenotyping
2. Liver biopsy:
   * +ve PAS
   * -ve diastase
   * Immunochemistry

Question 24

TTT of Chronic Hepatitis D2 Alpha 1 Anti-Trypsin Deficiency

Answer 24

Liver transplantation

Question 25

Ex in **Chronic Hepatitis D2 Gaucher Diseases**

Answer 25

1. Hepatosplenomegaly 2. Pancytopenia

Question 26

INvx for **Chronic Hepatitis D2 Gaucher Diseases**

Answer 26

1. Glucocerebrosidase: Decreased 2. Liver biopsy: Fibrosis & foam cells 3. CBC: Anemia & thrombocytopenia 4. Gene study

Question 27

TTT of **Chronic Hepatitis D2 Gaucher Diseases**

Answer 27

1. Bone marrow transplantation 2. Enzyme replacement "Cerezyme"

Question 28

Ex of **Chronic Hepatitis D2 Wilson Diseases**

Answer 28

1. Hepatic dysfunction 2. Neurological symptoms 3. Kaiser-Fleisher ring 4. Acute hemolytic crisis 5. Arthritis

Question 29

INVx for **Chronic Hepatitis D2 Wilson Diseases**

Answer 29

Question 30

TTT of **Chronic Hepatitis D2 Wilson Diseases**

Answer 30

1. Penicillamine "oral" 2. TETA "Tricyclic tetramine hydrochloride"

Question 31

Ex of **Chronic Hepatitis D2 Galactosemia**

Answer 31

1. Cataract 2. Mental retardation 3. Liver cirrhosis

Question 32

INVx for **Chronic Hepatitis D2 Galactosemia**

Question 33

TTT of **Chronic Hepatitis D2 Galactosemia**

Answer 33

1. Lactose free diet Milk & milk products → forbidden 2. Soy formula → may be used

Question 34

Ex of **Chronic Hepatitis D2 Glycogen storage Disesase**

Answer 34

Recurrent attacks of hypoglycemia

Question 35

TTT of **Chronic Hepatitis D2 Glycogen storage Disesase**

Answer 35

1. Nocturnal nasogastric infusion "to avoid hypoglycemia." 2. Cornstarch therapy

Question 35

INVx for **Chronic Hepatitis D2 Glycogen storage Disesase**

Answer 35

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