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Flashcards in Infectious hepatitis Deck (37):
1

Why can Hep A virus infect the gut so easily?

can withstand low pH

2

Hep A transmission route

fecal-oral

3

when high concentrations of viruses are shed in Hep A

3-10 days prior and just after clinical sx show

4

abrupt transision from well to illness

Hep A

5

gen sx of viral Hep (all strands)

RUQ pain
fever, malaise, myalgia, anorexia, N/V

6

what actually makes you sick in Hep A infection

immune response

7

dx for Hep A

IgM antibody against Hep A

8

Hep A endemic areas

worldwide

9

critical control measure for Hep A

handwashing after bowel movements and before food prep

10

transmission fof Hep E

fecal oral

11

10X more mortal than Hep A

hep E

12

serious risk population of Hep E

pregnant women

13

range of Hep E

worldwde, byt more serious risk in developing nations

14

primararly transferred by blood or blood products

Hep B

15

phase of Dane particle that is infectious

mature

16

forms Dane particles

Hep B

17

how is Hep B replication unique

involves DNA virus going through RNA intermediate using reverse transcriptidase

18

Hep strain that can cause cancer

Hep B

19

how can Hep B cause cancer

intergrates genome into chromosomal DNA of liver cells

20

sexually transmitted Hep

B

21

pathology cause of Hep B

cellularimmune response to viral antigens in the liver

22

1% of Hep B will progress to

severe fulminant hepatitis (often fatal)

23

defeinition of chronic Hep B

HBsAg found in the bloof for 6 months in the absence of detectable antibody

24

polyateritis nodusum and glomerulonephritis

chronic perisitant Heb B

25

marker of immunity to Heb B

precense of antibody to HBsAg

26

dx of Hep B

HBsAg in blood of individual presenting with acute hep sx

27

most important feature of HBV infection of the newborn

chronicity

28

control measures against Hep B

vaccination of high risk groups
immune globulin when needed
selection and screening of blood donors
education of healthcare workers and other high risk groups

29

treatment of chronic Hep B

alpha-interferon and lamivudine

30

Hep D needs what to be replicate

Hep B

31

important cause of fulminant hepatitis

Hep D

32

acute Hep B and antibody to Hep D

Hep D co-infection

33

sudden deteriioration in health of Hep B pt with ABsAg carrier state

Heb D superinfection

34

dx of chronic delta hep

HBsAg and high titers of antibody to HDV antigen

35

tranmission of Hep C

blood and blood products

36

dx of Hep C

ELISA and western blot

37

treatment of Hep C

pegelated interferon alpha and ribavarin