Head and Neck Flashcards

Describe the clinicopathologic features of benign head and neck tumors, squamous dysplasia, and carcinoma Compare and contrast the common salivary gland tumors Describe the clinicopathologic features of the common non-neoplastic diseases of the oral cavity (46 cards)

1
Q

diseases associated with aphthous ulcers

A

celiac, inflammatory bowel disease, Behcet disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

erthematous halo surrounding yellowish fibrinopurulent membrane

A

aphthous ulcers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

abrupt onset of vesicles throughout the oral cavity

A

acute herpetic gingivostomatitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

causes “cole sores”

A

HPV-1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

can reactivate HPV-1 sores

A

trauma, allergies, UV light, upper RTI, pregancy, menstruation, immunospuression, extremes of temp

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

balloning of infected cells with large eosinophillic intranuclear inclusions.Adjacent cells fuse to form large multinucleated polykarons

A

herpes lesions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

most common fungal infection of the oral cavity

A

candidiasis (thrush)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

can promote thrush

A

immunocompromise or broad spectrum antibiotics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

superfiscial curdlike inflamatory membrane of matted orginisms

A

thrush

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

submucosal nodular fibrous tissue formed by chronic irritation

A

fibromas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

common site of fibromas

A

buccal mucosa along bite line

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

treatment of fibromas

A

surgical exision and removal of source of irritation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

richly vascular, ulcerated lesions in the mouth

A

pyogenic granulomas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

white patch or plaque that cannot be scraped off and cannot be called anything else

A

leukoplakia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

may progress to SCC

A

leukoplakia, erythroplakia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

red velvety eroded area flat or depressed to the surrounding mucosa

A

erythroplakia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

risk factor of leukoplakia or erythroplakia

A

tobacco use

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

thickened, acanthotic, orderly mucosal lesions with marked dysplasia

A

leukoplasia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

most common oral cancer type

20
Q

mutations common in oral cancer caused by tobacco

A

TP53, p63 and NOTCH1

21
Q

most common behavioral risk factor of oral cancer

22
Q

cause of oral tumors in the tonsillar crypts and base of the tounge

A

HPV 16 infection

23
Q

mutation of oral tumors in the tonsillar crypts and base of the tounge

24
Q

worse prognosis of oral cancer

25
most common locations of oral SCC
ventral surface of the tounge, floor of mouth, lower lip, soft palate and gingiva
26
raised, firm, pearly plauqes
SCC
27
dry mouth resulting from decrease in saliva production
xerostomia
28
autoimmune disorder that can cause xerostomia
sjogren syndrome (occurs with dry eyes)
29
possible causes of xerostomia
many medications, sjogrens
30
dry eyes, dry mouth, inflammatory enlargement of salivary glands
sjogren syndrome
31
complications of xerostomia
cavities and difficulrt swallowing/speaking
32
most common cause of sialdenitis
mumps
33
imflamation fo salivary glands
sialadentitis
34
imflammatory lesion of salivary glands that changes in size in association with meals
mucocele
35
cystlike space lined with granulation tissue or fibrous connective tissue filled with mucin or macrophages
mucocele
36
common antecedent to sialadentitis
salivary stones, also food debris or edema from injury, dehydration, long term phenothiazene therapy
37
bugs that cause sialadentitis
staph A and strep viridens
38
most common salivary gland to get a tumor
parotid
39
the smaller the gland the more likely...
a tumor is malignant
40
most common type of salivary gland malignant tumor
mucoepidermoid carcinoma
41
most common salivary gland tumor
adenoma
42
tumor with mix of all kinds of cells
pleomorphic adenoma
43
long term risk of pleomorphic adenoma
can morph into very aggressive maligancu
44
variable mixture of squamous cells, mucus secreting cells, and intermediate cells
mucoepidermoid carcinoma
45
gene mutation in mucoepidermoid carcinoma
MAML2
46
cords, sheets and cysts lined by squamous, mucous or intermediate cells
mucoepidermoid carcinoma