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Flashcards in appendix and peritoneum Deck (32):
1

things that can obstruct the appendix

fecalith, gallstone, tumor, worms

2

process of acute appy

obstruction (possible) --> increased intra-luminal presure and collapse of draining veins --> ischemia, bacterial proliferation, further inflammation

3

key histological criterion of acute appy

neutrophils in the muscular wall

4

late result of untreated appy

rupture and peritonitis

5

sx of appy

n/v (,may come on later). anorexia, RLQ pain and tenderness at mcBurney point

6

complications of appy

perforation, pyleophlebitis and thrombosis of the portal venous drainage, liver abcess and bacteremia

7

ddx of appy

gasteroenteritis
ECTOPIC
meckel diverticulum
meserwnteric lyphadenitis
diverticulitis

8

appy tumor types (4)

carcinoid
mucocele
pseudomyxoma peritonei
adenocarcinoma

9

most common appy tumor

carcinoid

10

"salt and pepper" tumor with nests of tumor cells withut atypia and no mitosis

carcinoid

11

prognisis for carcinoid appy tumor

excellent

12

plump cells containing mucin vaculoes

goblet cell carcinoid

13

dilated appendix filled with mucin

mucocele

14

globular enlargement of the appy by mucus

simple mucocele

15

mucinous mucosa replaces the appendiceal mucosa. No malignant cells

benign mucinous cystadenoma

16

mucin-filled cystic dilation of appendix with pernetration of the appendiceal wall by invasive cells and spread beyond the appendix

malignant mucinous cystadenocarcinoma

17

ruptured mucinous cystadenocarcinoma can lead to

psuedomyxoma peritonei

18

psuedomyxoma peritonei prognosis

aggresive and fatal

19

mucin secretion that fills the peritoneum

psuedomyxoma peritonei

20

def of secondary peritonitis

perforation of hollow viscus with direct dissemination of contamiinated material

21

can cause sterile peritonitis

blood, bile, pancreatic fluid, drugs

22

can cause infective peritonitis

anything that pokes a hole in the GU tract

23

bugs that cause infective peritonitis

e coli, strep, gram neg rods, c perfringes

24

can cause spontaneus bacterial peritonitis

kids with nephrotic syndrome, cirrohis with ascites

25

possible outcomes of peritonitis

self-resolution
walled off abcesses
adhesions

26

tx of peritonitis

surgery, antibiotics, ICU and management of comorbidities

27

dense fibrous overgrowth of peritoneal retroperitoneal tissue

sclerosing retroperitonitis

28

can cause secondary peritoneal tumors

seeding and penetration from other sites (particularly the ovary and pancreas)

29

highly malignant peritoneal tumor in young males

desmoplastic small round cell

30

gene for desmoplastic small round cell tumor

EWS and WT1 gene fusion

31

firm hard neoplastic tissue with myxoid change and necrosis

desmoplastic small round cell tumor

32

aggregates of malignant small cells surrounded by a cellular desmoplastic stroma

desmoplastic small round cell tumor