Lecture 190 Flashcards

(52 cards)

1
Q

What is the average body temperature?

A

97.9F

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2
Q

A temperature range of 97.3F to 98.2F is considered normal for what population?

A

Healthy adults

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3
Q

What time of the day is the body temperature lowest?

A

Between 3-5am

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4
Q

What time of the day is the body temperature highest?

A

Between 4-6pm

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5
Q

A temperature range of 98.5F to 99.4F is considered normal for what population?

A

0-3 months old

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6
Q

A pediatric fever is defined as ____

A

100.4F

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7
Q

A doctor should be called for a fever in children <3 months old if their temperature reaches ____

A

100.4F or higher

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8
Q

A doctor should be called for a fever in children between 3-6 months old if the temperature is above ____

A

102F

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9
Q

A doctor should be called for a fever in children between 6-24 months old if their temperature is greater than ____ for longer than one day with no other signs or if greater than ____ with other signs

A

102F

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10
Q

A doctor should be called for a fever in children older than 2 years old if the fever lasts over ____

A

72 hours (3 days)

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11
Q

Strenuous exercise can elevate the temperature between ____

A

38-40C

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12
Q

Heat stroke can occur around ____

A

42-44C

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13
Q

Temperature regulation is impaired above ____

A

40C

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14
Q

The upper temperature limit of survival is ____

A

44C

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15
Q

Hypothermia begins below ____

A

35C

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16
Q

Temperature regulation is impaired below ____

A

34C

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17
Q

The lower temperature limit of survival is ____

A

30C

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18
Q

BMR/RMR is measured after a 12-hour fast, in the morning, and at a comfortable temperature, after how many minutes of rest?

A

30 minutes

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19
Q

How much of heat in the body is produced by the brain at rest?

A

16%

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20
Q

How much of heat in the body is produced by the trunk viscera at rest?

A

56%

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21
Q

Pheochromocytoma (adrenal tumor) can cause what clinical signs?

A

Weight loss and heat intolerance

22
Q

What hormone increases body temperature after ovulation?

23
Q

How much of heat in the body is produced by the muscle and skin during exercise?

24
Q

Where does chemical thermogenesis primarily take place?

A

Brown adipose tissue

25
____ is characterized by abundant lipid droplets and mitochondria
Brown adipose tissue
26
Mitochondria in BAT contain ____
Uncoupling protein 1 (UPC1)
27
What protein in the mitochondria of BAT uncouples the electrochemical proton gradient from ATP synthesis, causing energy to dissipate as heat?
Uncoupling protein 1
28
What triggers lipolysis in BAT?
Sympathetic activation
29
Shivering thermogenesis is mediated by what innervation?
Motor neuron innervation
30
What is cutaneous blood flow controlled by?
Sympathetic nervous system
31
____ acting on alpha 1 and alpha2 adrenergic receptors on vascular smooth muscle causes contraction
Norepinephrine (NE)
32
____ acting on ____ muscarinic receptors on vascular smooth muscle causes relaxation
Acetylcholine; M3
33
Sweat production occurs in ____ glands
Eccrine
34
What part of the eccrine glands produces a primary secretion?
Deep subdermal coil
35
What part of the eccrine glands reabsorbs sodium and chloride ions?
Duct
36
Rate of sweat production is determined by the level of ____ activation
Sympathetic
37
Sweat glands are innervated by post-ganglionic ____ neurons
Cholinergic sympathetic neurons
38
Reduced plasma volume activates the production of ____ by the adrenal gland
Aldosterone
39
Aldosterone causes an increase in ____ and ____ reabsorption in the kidney
Sodium and water reabsorption
40
Aldosterone upregulates the ____, enhancing sodium reabsorption within sweat gland luminal cells
Epithelial sodium channel (ENaC)
41
An unacclimated person can lose ____ grams of salt per day through sweat
15 to 30 grams
42
After how many weeks of acclimation is salt loss via sweat reduced to 3-5 grams/day?
4-6 weeks
43
Skin thermoreceptors are more sensitive to ____
Cold
44
Where are hypothalamic temperature-sensitive neurons located?
Preoptic area of the hypothalamus (POAH)
45
Hypothalamic temperature-sensitive neurons are warmth-sensitive neurons responsible for ____
Tcore sensation
46
What part of the hypothalamus contains thermogenesis command neurons?
Dorsomedial
47
What is the homeostatic mechanism in the hypothalamus that activates heat production and dissipation mechanisms to keep core temperature constant?
Hypothalamic set point
48
List 4 pyrogenic cytokines
IL-1, IL-6, TNF, and IFN
49
Cytokines act on the hypothalamic endothelium, leading to the production and release of ____
PGE2
50
____ acts on hypothalamic neurons to elevate the thermoregulatory set point
PGE2
51
What pharmaceutical can reduce fever by inhibiting the release of pyrogenetic cytokines?
Corticosteroids
52
Antipyretics inhibit COX, subsequently reducing the synthesis of ____ in the hypothalamus
PGE2