Lytic viruses Flashcards Preview

Immune Micro 3 > Lytic viruses > Flashcards

Flashcards in Lytic viruses Deck (17):
1

picornavirus physical properties

iscosahedral, +ssRNA, no lipid envelop, no tegument

2

poliovirus entry and genome release

injection into cytoplasm (nucleus not involved)

3

inapparent subclinical poliro

90-95% of infections, asymptomatic, virus from throat or stool

3

piconavirus diagnosis

isolation in CSF, stool, culture. Serum 4 fold rise in titer. PCR

3

genome, adenovirus

double stranded, unenveloped genome

4

picornavirus prevention mechanism Ribavirin

RNA depedent RNA polymerase inhibitors

5

paralytic poliomyelitis

asymmetric flaccid paralysis, lower extremities especially, bulbar paralysis, slow recovery with residual paralysis

7

aseptic meningitis, nonparalytic polio

minor progresses to CNS, stiff back and neck, 2-10 days then complete recovery

8

virus of common cold

rhinovirus

9

virus associated with gastroenteritis, myocarditis, encephalitis

Parechovirus

11

adenovirus diease

URI and occular > ecephalitis> GI and LRI > sytemic >genitourinary. 3-10 incubation, 6-9 days diarrhea

12

picornavirus prevention mechanism ruprintrivir

target protease processing

13

picornavirus prevention mechanism pleconaril

prevent entry and genome release

14

Mild polio

minor undifferentiated febrile illness, URI, influenza like

15

virus associated with paralysis, polio, common cold, meningitis, diarrhea, hand-foot-mout

enteroviruses

16

vvirus associated with hepatitis

hepatoviruses

17

virus associated with gastroenteritis

Kobuvirus