Flashcards in Muscle Path Quiz 4 Deck (21):
microscopic view of muscle atrophy (disuse atrophy)
diminished uptake of stain
diminished muscle mass
adipose tissue increases
the most common and one of the most serious forms of muscular dystrophy
Duchenne's is also called what? why is it called this?
because it looks like they have muscular calves, but muscle gets replaced by fat
Duchenne's is due to a defective gene on the X chromosome that leads to an inability to produce which protein?
inability to produce dystrophin in Duchenne's leads to what?
excess calcium enters cell causing cell death
An _______, Duchenne’s occurs almost exclusively _________
X-linked recessive disease; in boys
Myasthenia gravis is caused by
Abs that block Ach receptors
muscle weakness that worsens during periods of activity and improves after periods of rest is the hallmark for which disease?
thymoma is a rare tumor of the thymus gland associated with which condition?
which lab is routinely done in myasthenia gravis?
serum anti-acetylcholine receptor antibodies
Lambert-Eaton syndrome is associated with which cancer?
small cell lung cancer
Lambert-Eaton syndrome is caused by
Abs that block calcium channels
in Lambert-Eaton syndrome, the pre-synaptic block of calcium channels has what effect?
prevents release of Ach
Lymphocytes invade a myofiber in this skeletal muscle biopsy from a patient diagnosed with
In dermatomyositis, a characteristic __________ rash is usu present
Another type of rash associated with dermatomyositis is termed_________
shows up on dorsum of hands
what's a poor prognostic sign for polymyositis?
microscopic view of polymyositis reveals
Muscles fibers appear pale & enlarged
cellular invasion by macrophages
The biopsy appearance of inclusion body myositis is characterized by
focal areas of WBCs that invade muscle cell
Rhabdomyomas are benign tumors of what type of muscle?
where are they found
-head and neck