Peripheral Nervous System Path Quiz 5 Flashcards Preview

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Flashcards in Peripheral Nervous System Path Quiz 5 Deck (29):
1

Wallerian degeneration is a process that results when

a nerve fiber is cut or crushed, in which the part of the axon separated from the neuron's cell body degenerates distal to the injury.
occurs within 24-36 hrs

2

Bell's palsy involves which cranial nerve?

facial nerve

3

how to differentiate a stroke from Bell's palsy?

stroke- can wrinkle forehead
BP- can't wrinkle forehead

4

associated etiology for bell's palsy?

HSV1

5

many cases of trigeminal neuralgia are caused by

blood vessel compression of the trigeminal nerve root at the pons

6

oculomotor nerve palsy is also known by which sx?

“down and out” symptoms,
lateral downward deviation

7

in carpal tunnel syndrome you have sx along which nerve?

median nerve

8

what's the hallmark sign of carpal tunnel syndrome?

thenar eminence atrophy

9

what's the characteristic sign of ulnar nevre injury or ulnar nerve palsy?

claw hand deformity
sx affecting 4th and 5th digits

10

Meralgia paresthetica affects which nerve?

lateral cutaneous nerve of the thigh

11

Meralgia paresthetica is more common in obese patients. why?

increased mechanical stress on the inguinal ligament

12

presumed pathogenesis of diabetic neuropathy?

sorbitol and inositol
ischemia
microvascular disease

13

the most common cause of immune or inflammatory polyneuropathies is

Guillain-Barré syndrome (GBS)

14

Guillain-Barré syndrome (GBS) is characterized by

ascending paralysis

15

Botulism is characterized by

descending paralysis

16

which vitamin deficiency is tied to neuropathy?

Vit B1 (thiamin)

17

a vitamin B1 deficiency that causes neuropathy is called?

Beriberi

18

pathogenesis of botulism

botulinum toxin blocks presynaptic nerve preventing release of Ach
its NOT Ab mediated

19

what bugger cause leprosy?

Mycobacterium leprae

20

Mycobacterium leprae under microscope

bacilli-shaped bacterium that doesn’t take up stain very well, unless treated with acid (acid fast)

21

how does lyme differ from bell's palsy?

Lyme is a bilateral facial neuropathy

22

microscopic appearance of herpes zoster lesion

multinucleated giant cell

23

shingles at the tip of the nose

Hutchinson's sign

24

acoustic neuroma (a vestibular schwannoma) involves which nerve?

verstibulocochlear nerve (CN VIII)

25

microscopically neurofibroma appears

spindle shaped
darkly staining
large cells

26

Neurofibromatosis type 1 is characterized by

multiple small cutaneous neurofibromas
cafe au lait spots

27

Neurofibromatosis type 2 is the result of a mutation of which protein?

protein merlin

28

hallmark of neurofibromatosis type 2 is

hearing loss due to acoustic neuromas around the age of twenty

29

perineuromas are characterized by

elongated cells in parallel bundles