Joint Path Quiz 4 Flashcards Preview

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Flashcards in Joint Path Quiz 4 Deck (23):
1

most common cause of secondary osteoarthritis?

DM
also hemochromatosis and Wilson's disease

2

x-ray of OA shows

jnt space narrowing
osteophyte formation (bony outgrowths)
subchondral bone cysts
sclerosis

3

Hands of person with OA classically shows

Herbeden nodes distally (DIPs)
Bouchard's nodes proximally (PIPs)

4

RA is characterized as

an auto-immune disease

5

RA is commonly (~ 80% of cases) associated with a group of anti-IgG autoantibodies called

rheumatoid factors (RF)

6

in RA, what changes are taking place at the level of the joint?

the synovial membrane becomes grossly enlarged, congested, edematous, and thickened

7

microscopically RA appears with

multiple layers of proliferation of synoviocytes

8

which lab IS highly specific for RA?

anti-CCP (aka ACPAs)

9

what x-ray finding is characteristic for ankylosing spondylitis?

"bamboo spine"
due to vertebral body fusion

10

Reactive arthritis is known for which constellation of sx?

arthritis, non-gonococcal urethritis or cervicitis, and conjunctivitis

11

reactive arthritis is due to either GI infection or GU infection. Which bug is the most commonly associated GU infection?

Chlamydia

12

which rash is associated with reactive arthritis?

keratoderma blennorrhagicum

13

what is are two distinctive features of psoriatic arthritis?

nail pitting
onycholysis

14

the number one cause of septic arthritis (aka supperative arthritis) in adults?

staphylococcus

15

the number one cause of septic arthritis (aka supperative arthritis) in children?

H. influenza

16

the number one cause of septic arthritis (aka supperative arthritis) in elderly?

E. coli

17

distinguish septic arthritis from reactive arthritis

reactive arthritis refers to arthritis cause by an immune consequence of an infection, but not directly attributable to the infection itself
septic arthritis is the direct invasion of a joint by an infectious agent

18

the number one cause of septic arthritis in young adults?

neisseria gonorrhoea

19

Pott's disease is characterized by

TB of the spine

20

what's the characteristic rash of Lyme disease?

Erythema migrans

21

gout caused by

uric acid crystals (aka monosodium urate)

22

pseudogout caused by

calcium pyrophosphate crystals

23

most common benign tumor of the joints?

ganglion