Flashcards in Joint Path Quiz 4 Deck (23):
most common cause of secondary osteoarthritis?
also hemochromatosis and Wilson's disease
x-ray of OA shows
jnt space narrowing
osteophyte formation (bony outgrowths)
subchondral bone cysts
Hands of person with OA classically shows
Herbeden nodes distally (DIPs)
Bouchard's nodes proximally (PIPs)
RA is characterized as
an auto-immune disease
RA is commonly (~ 80% of cases) associated with a group of anti-IgG autoantibodies called
rheumatoid factors (RF)
in RA, what changes are taking place at the level of the joint?
the synovial membrane becomes grossly enlarged, congested, edematous, and thickened
microscopically RA appears with
multiple layers of proliferation of synoviocytes
which lab IS highly specific for RA?
anti-CCP (aka ACPAs)
what x-ray finding is characteristic for ankylosing spondylitis?
due to vertebral body fusion
Reactive arthritis is known for which constellation of sx?
arthritis, non-gonococcal urethritis or cervicitis, and conjunctivitis
reactive arthritis is due to either GI infection or GU infection. Which bug is the most commonly associated GU infection?
which rash is associated with reactive arthritis?
what is are two distinctive features of psoriatic arthritis?
the number one cause of septic arthritis (aka supperative arthritis) in adults?
the number one cause of septic arthritis (aka supperative arthritis) in children?
the number one cause of septic arthritis (aka supperative arthritis) in elderly?
distinguish septic arthritis from reactive arthritis
reactive arthritis refers to arthritis cause by an immune consequence of an infection, but not directly attributable to the infection itself
septic arthritis is the direct invasion of a joint by an infectious agent
the number one cause of septic arthritis in young adults?
Pott's disease is characterized by
TB of the spine
what's the characteristic rash of Lyme disease?
gout caused by
uric acid crystals (aka monosodium urate)
pseudogout caused by
calcium pyrophosphate crystals