Proteins 1 Flashcards

1
Q

What is the process of protein synthesis?

A

DNA -Transcription-> RNA -Translation-> Protein

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2
Q

Define a codon.

A

Defined by the initial nucleotide from which translation starts.

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3
Q

Define a peptide bond.

A

The formation of a covalent bond with the loss of one molecule of water.

H O
| ||
Nā€”-C

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4
Q

What is primary structure?

A

The sequence of amino acids in a polypeptide chain.

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5
Q

What is secondary structure?

A

The spacial arrangement of amino acid residues that are near each other in the linear sequence.

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6
Q

What are the two types of secondary structure?

A

Alpha helixes which are held together by hydrogen bonds between the N-H and O=C of the next group.

Beta plated sheets which are held together by hydrogen bonds between the amide groups.

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7
Q

What is tertiary structure?

A

The spatial arrangement of amino acid residues that are far apart in a linear sequence.

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8
Q

What are the 5 types of bonding in tertiary/quaternary structure?

A
Van Der Waals
Ionic interactions
Hydrogen bonds
Disulfide bridges
Hydrophobic interactions
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9
Q

What is quaternary structure?

A

Refers to the spatial arrangement of individual polypeptide chains in a multi-subunit protein.

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