Carbohydrates 5

Question 1

Define the citric acid cycle.

Answer 1

Common metabolic pathway for all fuel molecules. Occurs in the mitochondrial matrix and yields a large amount of energy.

Question 2

The citric acid cycle removes electrons and passes them to ______ and ______.

Answer 2

NAD+ and FAD+

Question 3

What is acetyl CoA made of?

Answer 3

Pyruvate and fatty acids.

Question 4

What are the 3 steps of making acetyl CoA?

Answer 4

Decarboxylation
Oxidation
Transfer of CoA complex

Question 5

Define pyruvate dehydrogenase.

Answer 5

Contains 10 copies of each enzyme subunit and each subunit catalyses a different part of the reaction.

Question 6

Why is the ‘black box’ of the citric acid cycle termed that?

Answer 6

The intermediate molecules in the cycle remain constant.

Question 7

GTP can readily be converted into ______.

Answer 7

ATP

Question 8

What regulates pyruvate dehydrogenase?

Answer 8

Intermediate products and the end point of cellular respiration

Question 9

What regulates isocitrate dehydrogenase?

Answer 9

ATP/NADH negatively regulate

ADP positively regulates

Question 10

What regulates Alpha-ketoglutarate dehydrogenase?

Answer 10

NADH/Succinyl CoA negatively regulate

ATP positively regulates

Question 11

The citric acid cycle is ______.

Answer 11

Amphibolic

Question 12

What does blocking isocitrate cause?

Answer 12

Build up of citrate which is shuttled to the cytoplasm and stops glycolysis.

Question 13

What does build up of alpha-ketoglutarate cause?

Answer 13

Switches its use to production of amino acids.