Carbohydrates 5 Flashcards Preview

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Flashcards in Carbohydrates 5 Deck (13)
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1
Q

Define the citric acid cycle.

A

Common metabolic pathway for all fuel molecules. Occurs in the mitochondrial matrix and yields a large amount of energy.

2
Q

The citric acid cycle removes electrons and passes them to ______ and ______.

A

NAD+ and FAD+

3
Q

What is acetyl CoA made of?

A

Pyruvate and fatty acids.

4
Q

What are the 3 steps of making acetyl CoA?

A

Decarboxylation
Oxidation
Transfer of CoA complex

5
Q

Define pyruvate dehydrogenase.

A

Contains 10 copies of each enzyme subunit and each subunit catalyses a different part of the reaction.

6
Q

Why is the ‘black box’ of the citric acid cycle termed that?

A

The intermediate molecules in the cycle remain constant.

7
Q

GTP can readily be converted into ______.

A

ATP

8
Q

What regulates pyruvate dehydrogenase?

A

Intermediate products and the end point of cellular respiration

9
Q

What regulates isocitrate dehydrogenase?

A

ATP/NADH negatively regulate

ADP positively regulates

10
Q

What regulates Alpha-ketoglutarate dehydrogenase?

A

NADH/Succinyl CoA negatively regulate

ATP positively regulates

11
Q

The citric acid cycle is ______.

A

Amphibolic

12
Q

What does blocking isocitrate cause?

A

Build up of citrate which is shuttled to the cytoplasm and stops glycolysis.

13
Q

What does build up of alpha-ketoglutarate cause?

A

Switches its use to production of amino acids.