seronegative spondyloarthropathies Flashcards Preview

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Flashcards in seronegative spondyloarthropathies Deck (12):
1

psoriatic arthritis

joint pain and stiffness associated with psoriasis
asymmetric and patchy involvement. dactylitis (sausage fingers) and pencil-in-cup deformity on x ray. fewer than 1/3 of pts with psoriasis

2

ankylosing spondylitis

spine and sacroiliac joint disease. see stiff spine from joint fusion (bamboo spine), uveitis, and aortic regurg

3

What infections may be followed by reactive arthrits?

GI (shigella, salmonella, yersinia, campylobacter) or chlamydia

4

What do you see in sarcoidosis?

widespread non-caseating granulomas and elevated serum ACE levels

5

What are some symptoms in sarcoid?

restrictive lung disease, erythema nodosum, lupus pernio, Bell palsy, epitheliod granulomas with asteroid bodies, uveitis, and hyper calcemia (d/t vitamin D activation in macrophates)

6

Polymyalgia rheumatica. what is it associated with?

pain and stiffness in shoulders and hips, often with fever, malaise, and weight loss. no weakness. associated with giant cell arteritis.

7

Findings and treatments for polymyalgia rheumatica

incr. ESR, incr CRP, normal CK. give low-dose corticosteroids

8

With what other problem is myasthenia gravis often associated?

thymoma

9

lambert-eaton

ab against the calcium channel in the presynaptic terminal
proximal muscles involved and eyes usually spared
typically a paraneoplastic syndrome related to small cell carcinoma
improves with use.

10

What is the typical cell of liposcarcoma

lipoblast

11

What is associated with a rhabdomyoma?

tuberous sclerosis

12

What is one feature of rhabdomyosarcoma cells? what are the most common sites? how does patient influence that?

desmin positive rhabdomyoblast. most common site is the head and neck. seen in the vagina of young girls

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