seronegative spondyloarthropathies Flashcards Preview

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Flashcards in seronegative spondyloarthropathies Deck (12)
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1
Q

psoriatic arthritis

A

joint pain and stiffness associated with psoriasis
asymmetric and patchy involvement. dactylitis (sausage fingers) and pencil-in-cup deformity on x ray. fewer than 1/3 of pts with psoriasis

2
Q

ankylosing spondylitis

A

spine and sacroiliac joint disease. see stiff spine from joint fusion (bamboo spine), uveitis, and aortic regurg

3
Q

What infections may be followed by reactive arthrits?

A

GI (shigella, salmonella, yersinia, campylobacter) or chlamydia

4
Q

What do you see in sarcoidosis?

A

widespread non-caseating granulomas and elevated serum ACE levels

5
Q

What are some symptoms in sarcoid?

A

restrictive lung disease, erythema nodosum, lupus pernio, Bell palsy, epitheliod granulomas with asteroid bodies, uveitis, and hyper calcemia (d/t vitamin D activation in macrophates)

6
Q

Polymyalgia rheumatica. what is it associated with?

A

pain and stiffness in shoulders and hips, often with fever, malaise, and weight loss. no weakness. associated with giant cell arteritis.

7
Q

Findings and treatments for polymyalgia rheumatica

A

incr. ESR, incr CRP, normal CK. give low-dose corticosteroids

8
Q

With what other problem is myasthenia gravis often associated?

A

thymoma

9
Q

lambert-eaton

A

ab against the calcium channel in the presynaptic terminal
proximal muscles involved and eyes usually spared
typically a paraneoplastic syndrome related to small cell carcinoma
improves with use.

10
Q

What is the typical cell of liposcarcoma

A

lipoblast

11
Q

What is associated with a rhabdomyoma?

A

tuberous sclerosis

12
Q

What is one feature of rhabdomyosarcoma cells? what are the most common sites? how does patient influence that?

A

desmin positive rhabdomyoblast. most common site is the head and neck. seen in the vagina of young girls

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