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Anatomic Pathology 2 > Species specific renal disorders > Flashcards

Species specific renal disorders Flashcards

1
Q

What urinary tract diseases are commonly associated with dogs?

A

leptospirosis, lyme’s nephritis, canine herpe’s virus disease, renal dysplasia, toxic tubular necrosis, membranous glomerulonephritis, amyloidosis, urolithiasis, cystitis, transitional cell carcinoma, and renal lymphosarcoma

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2
Q

What lesions does acute leptospirosis cause in dogs?

A

hemoglobinuric nephrosis and acute tubulointerstitial nephritis

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3
Q

What strains of bacteria commonly cause acute leptospirosis in dogs?

A

L. canicola and L. icterohemorrhagica

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4
Q

What lesions does chronic leptospirosis cause in dogs?

A

azotemia, polyuria, isosthenuria, bacteriuria, enlarged nodlar kidneys, lymphogranulomatous and purulent tubulointerstitial nephritis and spirochetes within tubule lumens

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5
Q

What strains of bacteria commonly cause chronic leptospirosis in dogs?

A

L. grippotyphosa and L. bratislava

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6
Q

What phase of Lyme’s disease causes Lyme’s nephritis?

A

the chronic phase

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7
Q

What lesions does Lyme’s nephritis cause?

A

membranoproliferative glomerulonephritis +/- intersitital nephritis

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8
Q

What bacteria commonly causes Lyme’s nephritis?

A

Borrelia burgdorferi

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9
Q

How is canine herpesvirus disease transmitted and what dogs are commonly effected by it?

A

it is transmitted from bitch to pup and it usually effects puppies less than 3 weeks of age

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10
Q

Why are puppies less than 3 weeks of age susceptible to canine herpesvirus disease?

A

because they cannot regulate their body temperature at this time and the virus replicates at a lowered temperature so if the pup is neglected by the mother there is a chance that the pups temp will get too low

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11
Q

What type of defect is renal dysplasia?

A

it is a congenital/neonatal defect that is inherited in several breeds

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12
Q

What clinical syndrome is associated with renal dysplasia?

A

chronic renal failure by 3 years of age

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13
Q

What lesions are associated with renal dysplasia?

A

small, segmentally fibrotic kidneys, fetal glomeruli, metanephric ducts, fibrosis, and supernephrons

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14
Q

What is cystitis in dogs commonly caused by?

A

ascending bacterial infection

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15
Q

What urinary tract diseases are commonly associated with cats?

A

urolithiasis, feline urologic syndrome/chronic cystitis, toxic tubular necrosis, feline infectious peritonitis, renal lymphosarcoma and chronic glomerulonephritis

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16
Q

What are struvites in cats commonly composed of?

A

fine sand-like crystals and a mucous matrix

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17
Q

Why do male cats commonly get urethral obstruction?

A

because their urethra is very narrow

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18
Q

What lesions are associated with urolithiasis in cats?

A

marked urinary bladder distention with hemorrhagic cystitis

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19
Q

What clinical syndromes can cats with urethral obstruction acquire?

A

post-renal azotemia and hyperkalemia-the hyperkalemia can cause bradycardia and death

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20
Q

What lesions can feline urologic syndrome cause?

A

mild recurrent hemorrhagic cystitis

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21
Q

What can cause toxic tubular necrosis in cats?

A

ethylene glycol and easter lilies

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22
Q

What lesions and clinical syndroms are often associated with toxic tubular necrosis?

A

acute proximal convoluted tubule necrosis and acute renal azotemia/acute renal failure

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23
Q

What is feline infectious peritonitis?

A

multisystemic disease caused by FIP coronavirus

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24
Q

What lesions are associated with feline infectious peritonitis?

A

immune-mediated phlebitis/vasculitis, lymphoplasmacytic to pyogranulomatous vasculocentric exudate, and segmental, white nodular lesions along subcapsular and arcuate veins

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25
Q

What appearance does renal lymphosarcoma give kidneys in cats?

A

nodular to diffuse effacement of renal cortex

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26
Q

What urinary tract diseases are commonly associated with horses?

A

actinobacillosis, renal crest necrosis, equine infectious anemia, and toxic tubular necrosis

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27
Q

What horses are specifically effected by actinobacillus?

A

foals

28
Q

What characteristic lesion is associated with actinobacillosis?

A

multiple small abscesses throughout the kidney

29
Q

Microscopically what do you see with actinobacillosis?

A

colonies of bacteria in capillaries and glomeruli

30
Q

What lesion is associated with renal crest necrosis?

A

coagulative necrosis

31
Q

What commonly causes renal crest necrosis in horses?

A

NSAIDS and dehydration

32
Q

What is the cause of equine infectious anemia?

A

equine infectious anemia retrovirus

33
Q

What lesion is associated with equine infectious anemia?

A

glomerulonephritis and lymphoplasmacytic interstitial nephritis

34
Q

What urinary tract diseases are commonly associated with cattle?

A

urolithiasis, pyelonephritis, lymphosarcoma, and bracken fern poisoning

35
Q

What cattle specifically are affectedby urolithiasis?

A

feedlot calves and steers

36
Q

What is ‘water belly’?

A

the result of an obstruction in the sigmoid flexure leading to a ruptured bladder and urine accumulates on the ventral part of the abdomen

37
Q

What is pyelonephritis a consequence of in cattle?

A

impedence of urine flow

38
Q

What bacteria is commonly associated with pyelonephritis in cattle?

A

C. renale

39
Q

What does bracken fern poisoning cause?

A

chronic hemorrhagic cystitis and can cause transitional cell carcinoma

40
Q

What urinary tract diseases are commonly associated with ovine?

A

copper toxicosis and urolithiasis

41
Q

How does copper toxicosis happen?

A

copper accumulates in the liver and some stimulus, maybe stress, can cause a massive release of copper from the liver causing acute hemolysis

42
Q

What lesion is associated with copper toxicosis?

A

hemoglobinuric nephropathy - the kidney becomes dark red or blue

43
Q

What urinary tract diseases are commonly associated with pigs?

A

pyelonephritis, leptospirosis, PRRS virus, acute multifocal hemorrhage

44
Q

What lesion does PRRS virus cause?

A

interstitial nephritis

45
Q

What can cause acute multifocal renal hemorrhage in swine?

A

septicemia (salmonellosis, actinobacillosis, acue erysipelas) or viremia (classic swine fever or african swine fever)

46
Q

What lesion is shown here?

A

lymphohistiocytic tubulointerstitial nephritis due to leptospira bratislava

47
Q

What is shown here?

A

exudate - neutrophil infiltrate

48
Q

What is shown here?

A

nest of spirochetes along the brush border

49
Q

What lesion is shown here?

A

chronic membranoproliferative glomerulonephritis and interstitial nephritis due to lyme’s disease

50
Q

What lesion is shown here?

A

membranoproliferative glomerulonephritis - Lyme’s disease

51
Q

What lesion is shown here?

A

membranoproliferative glomerulonephritis - Lyme’s disease

52
Q

What lesion is shown here?

A

multifocal necrohemorrhagic nephritis due to canine herpesvirus

53
Q

What lesion is shown here?

A

hemorrhagic cystitis with bladder distention in an obstructed tomcat

54
Q

What lesion is shown here?

A

multifocal pyogranulomatous vasculocentric nephritis

55
Q

What lesion is shown here?

A

renal lymphosarcoma

56
Q

What lesion is shown here?

A

lymphosarcoma

57
Q

What lesion is shown here?

A

acute multifocal purulent nephritis due to actinobacillus equuli

58
Q

What lesion is shown here?

A

acute multifocal purulent nephritis due to actinovacillus equuli in a foal

59
Q

What is shown here?

A

bacteria

60
Q

What is shown here?

A

hemorrhage

61
Q

What lesion is shown here?

A

renal crest necrosis

62
Q

What lesion is shown here?

A

subacute purulent pyelonephritis

63
Q

What lesion is shown here?

A

chronic pyelonephritis

64
Q

What lesion is shown here?

A

subacute bilateral diffuse necropurulent pyelonephritis and acute locally extensive fibronecrotic cystitis, secondary to urolithiasis and obstruction

65
Q

What lesion is shown here?

A

renal lymphosarcoma in a cow

66
Q

What lesion is shown here?

A

hemoglobin nephropathy secondary to copper toxicosis in sheep

67
Q

What lesion is shown here?

A

acute multifocal renal petechia due to septicemic salmonellosis in a pig

Anatomic Pathology 2 (48 decks)

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