Test 2 - Insulin (Josh) Flashcards Preview

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Flashcards in Test 2 - Insulin (Josh) Deck (33)
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1
Q

Short Duration: Rapid Acting insulins:

A

LOGs don’t LAG when rolling down a hill

  • Lispro (HumaLOG)
  • Aspart (NovoLOG)
  • Glulisine (Apidra)
2
Q

Which insulin can be administered IM?

A

Regular (Humulin R, Novolin R)

rarely done

3
Q

Can Short Duration: Rapid Acting insulins be administered IV?

A

yes, but rarely done

4
Q

A subQ injection of —— should be given within 15 mins before meals

A subQ injection of —– should be given 5-10 mins before meals

A subQ injection of —– should be given within 15 mins before or within 20 mins after meals.

A

Lispro (HumaLOG)

5
Q

Which insulins are Short Duration: Slower Acting?

A

Regular (Humulin R, Novolin R)

6
Q

Short Duration Insulins:

A

Rapid Acting: lispro, aspart, glulisine

Shorter Acting: regular

7
Q

—— should be injected subQ ~30 mins before meals.

A

Regular Insulin (Humulin R, Novolin R)

8
Q

Which insulin is given IV for emergencies?

A

Regular Insulin (Humulin R, Novolin R)

never give U-500 in IV

9
Q

Which insulin can come in U-500 and U-100 strength?

A

Regular Insulin (Humulin R, Novolin R)

all others are U-100

10
Q

Which insulin is administered subQ twice a day at the same time?

A

NPH (Humulin N, Novolin N)

11
Q

Which insulins are OTC?

A

NPH (Humulin N, Novolin N)

Regular (Humulin R, Novolin R)

12
Q

NPH is in which class of insulins?

A

iNtermediate Acting

give it twice a day at the same time every day

13
Q

Which class of insulin can be given once (or twice) a day (at the same time)?

A

Long Duration

  • Glargine (Lantus)
  • Detemir (Levemir)
14
Q

What are the seven types of insulin we need to know?

A

1) Lispro (HumaLOG)
2) Aspart (NovoLOG)
3) Glulisine (Apidra)
4) Regular (Humulin R, Novolin R)
5) NPH (Humulin N, Novolin N)
6) Glargine (Lantus)
7) Detemir (Levemir)

15
Q

Onset: 15-30 mins
Peak: 0.5-2.5 hrs
Duration: 3-6 hr

A

Lispro (HumaLOG)

16
Q

Onset: 10-20 mins
Peak: 1-3 hrs
Duration: 3-5 hr

A

Aspart (NovoLOG)

17
Q

Onset: 10-15 mins
Peak: 1-1.5 hrs
Duration: 3-5 hr

A

Glulisine (Apidra)

18
Q

Onset: 30-60 mins
Peak: 1-5 hrs
Duration: 6-10 hr

A

Regular (Humulin R, Novolin R)

19
Q

Onset: 60-120 mins
Peak: 6-14 hrs
Duration: 16-24 hr

A

NPH (Humulin N, Novolin N)

20
Q

Onset: 70 mins
Peak: none (levels are steady; no peak)
Duration: 18-24 hr

A

Glargine (Lantus)

21
Q

Onset: 60-120 mins
Peak: 12-24 hrs
Duration: varies (dose dependent)

A

Detemir (Levemir)

22
Q

Which insulin has no peak (i.e.: levels stay steady during the whole duration of the drug)?

A

Glargine (Lantus)

Long-duration insulin

23
Q

Only —– is appropriate for mixing w/ short-acting insulins.

A

NPH

ex: 70% NPH/30% Regular (Humulin 70/30) or Novolin 70/30)

24
Q

NPH means — —- —-

A

Neutral Protamine Hagedorn

25
Q

What is the most common and serious side effect of insulin?

A

Hypoglycemia

b/c the insulin is stimulating uptake of the blood sugar into the muscle cells, lowering serum blood sugar

remember the first adverse effect of all drugs is if they WORK TOO WELL

26
Q

Hypoglycemia is a blood sugar below —-

A

70 mg/dL

27
Q

Why does hypoglycemia look like sympathetic stuff?

A

when glucose falls rapidly, activation of sympathetic nervous system leads to tachycardia, palpitations, sweating & nervousness

28
Q

CNS issues, like fatigue, headache, confusion and drowsiness happen when….

A

blood sugar falls GRADUALLY

29
Q

SNS issues, like tachycardia, sweating and palpitations, happen when….

A

blood sugar falls RAPIDLY

30
Q

Insulin in —– should be stored in —— until needed.

Insulin in —– can be kept at room temp for up to ——

A

unopened vials

refrigerator

vial currently used

1 month

31
Q

Mixtures of insulin in —— are stable for —– at room temp and —– if refrigerated

A

vials

1 month

3 months

32
Q

Mixture of insulin in —– should be stored in the fridge for —–

A

pre-filled syringes

1 (possibly 2) weeks

33
Q

If patient doesn’t rotate injection sites, what can happen?

A

lypodistrophy (destruction of adipose tissue)