Neoplasia L27

Question 1

What is neoplasia?

Answer 1

Neoplasia is an abnormality of cell growth and multiplication characterised by the following:

• excessive cellular proliferation usually producing a tumour.
• uncoordinated growth occurring without apparent purpose
• persistence of excessive cell proliferation and growth even after inciting stimulus is removed

Question 2

What is neoplasia described as on a molecular level?

Answer 2

A disorder of growth regulatory genes

Question 3

What can neoplasia be triggered by?

Answer 3

Viruses
Hereditary factors 
Failure of the immune system 
Chemical carcinogens 
Exposure to UV or X-ray radiation

Question 4

How can neoplasms be classified?

Answer 4

By site of origin

Biological behaviour- i.e. melignant or benign

Question 5

What does it mean to have a benign tumour?

Answer 5

A tumour that stays at site of origin - less dangerous than malignant tumours however damage by compressing neighbouring tissue.

Question 6

What is dangerous about malignant tumours?

Answer 6

They are metastatic and so spread alongside having a rapid growth and spreading effect.

Question 7

Can you get tumours that are in between malignant and benign?

Answer 7

Yes

Question 8

What is cancer of a neural cell called?

Answer 8

Neuroma

Question 9

What is cancer of a fat cell called?

Answer 9

Lipoma/liposarcoma

Question 10

What is cancer of a glandular ( e.g liver, renal, endocrine) cell called?

Answer 10

Adenoma/adenocarcinoma

Question 11

What is cancer of the bones called?

Answer 11

Osteoma / Osteosarcoma

Question 12

What is cancer of schwaan cells called?

Answer 12

Schwannoma

Question 13

What is cancer of the meninges called?

Answer 13

Meningioma

Question 14

What is the most common ocular tumour?

Answer 14

Melanoma

Question 15

How can intercranial tumours affect vision?

Answer 15

They can affect any point in the visual pathway