L49 Iris Flashcards

You may prefer our related Brainscape-certified flashcards:
1
Q

What is the pupilary zone?

A

The bit of the iris closest to the pupil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the Ciliary zone?

A

The bit of the iris closest to the ciliary body

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the collarette?

A

The bit of the iris where the pupillary zone merges into the ciliary zone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Familiarise yourself with this clear diagram.

What can you not see in the diagram?

A

Ora Serrata and structures further to the left.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Where is the iris thinnest?

A

Where it comes off the ciliary body - this is known as the iris root.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Where is the iris thickest?

A

In the region of the collarette

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the back surface of the iris covered in and how does that relate to the ciliary body.?

A

Present at the back surface of the eye is the Posterior double pigmented epithelium.

The ciliary body contains a double pigmented epithelium that merges at the iris root with the double epithelium at the back of the iris.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the difference between the bilayer epithelium of the ciliary body and the back surface of the iris?

A

The bi-layer epithelium of the ciliary body contained an outer pigmented layer and inner unpigmented layer whereas, the bi-layer epithelium of the iris contains two pigmented epithelium. (no unpigmented layer in the back surface of the iris.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Why are both layers of the back surface of the iris pigmented?

A

The function of the iris is to make the pupil (aperture stop) thus you want it to block light

It is to stop light getting through so that the pupil can act as an aperture stop.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

How are pigment epithelial layers of the iris held together and why?

A

Interdigitating microvilli between pigment epithelial layers of the iris as well as adhering junctions, gap junctions, and desmosomes.

These exist as the iris is constantly contracting and expanding and so you don’t want these layers to separate.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is that ring of pigment around the pupil of the eye?

A

It is called the pupillary ruff. It is the double pigmented epithelium from the rear surface of the iris that ‘peeps’ up through the iris.

(everyone has this even those with blue or other coloured eyes).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What does the pupillary ruff look like in person?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Why is the iris dilator/dilatator (you can refer to it as either one of the two) unusual (not unique)?

A

Because the dilator muscle is within the epithelial cells. Said to be myoepithelial.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

How do the two layers of the rear surface iris epithelium differ?

A

The most posterior epithelial layer is 100% pigmented whereas the anterior epithelial layer is half pigmented half dilator muscle (it is myoepithelial).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What kind of muscle is the iris dilator muscle?

And what is it innervated by?

A

A radial muscle and its contraction thus results in pupil dilation.

It is smooth muscle so it is innervated by the autonomic nervous system and is innervated by the sympathetic system.

(to remember this think - wide-eyed with fear- to associate with the sympathetic system).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Connective tissue can either be dense or loose - depending on what?

A

Depending on whether collagen is tightly packed toegther or loosely arranged.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Is the iris stroma dense or loose (areolar) connective tissue?

A

Loose connective tissue - has the consistency of a sponge (areolar). (as its full of holes and aquous humour infiltrates the loose connective tissue of the stroma).

18
Q

What kind of muscle is the iris sphincter muscle and where is it located?

A

It is a smooth muscle (circular muscle) and it is located at the tip of the iris (different to dilator muscle as its not part of the epithelium).

19
Q

What kind of muscle is the iris sphincter muscle and what happens when it contracts?

How is it innervated?

A

It is a circular smooth muscle. When it contracts the pupil constricts.

It is parasympathetically innervated.

20
Q

How wide is the iris sphincter?

A

Less than 1mm- its on average 0.75 mm.

21
Q

Where is the major iridic circle found?

A

At the root of the iris.

22
Q

What two blood vessels does the major iridic circle receive input from?

A

Posterior ciliary artery / long ciliary artery

&

the anterior ciliary artery.

23
Q

Vessels from what run up the iris?

A

The major iridic circle

24
Q

When the pupil is constricted how are the vessels?

A

They run roughly straight as can be seen in a fluorescine angiogram (basically putting flurorescine in to see a structure and then examining under UV light).

25
Q

What is a key property of the capillaries in the ciliary body and why?

A

They are very fenestrated as they are involved in aqueous production.

26
Q

In the iris are blood vessels fenestrated?

A

No

27
Q

What can sometimes be found surrounding blood vessels in the eye?

A

Pericytes - Pericytes are cells that wrap around the endothelial cells that line the capillaries and venules throughout the body.

These make the vessels water tight.

28
Q

Why are blood vessels in the iris not fenestrated and sometimes even covered in pericytes?

A

Because you don’t want the exchange of aqueous happening in the iris.

The other advantage of pericytes is that you almost have a tube within a tube and that means that when the iris contracts and dilates you won’t get kinking of the arteries so the blood supply won’t be cut off because they are protected by this layer of pericytes.

29
Q

What is present in the iris stroma?

A

Loosely arranged collagen - so things like fibroblasts and mast cells.

blood vessels

And CLUMP CELLS.

30
Q

What are clump cells?

A

Large cells working as macrophages which are packed full of melanin (more so than melanocytes).

31
Q

How does the number and size of clump cells change with age?

A

The number and size of clump cells increase with age.

32
Q

What is the function of clump cells?

A

To keep the aqueous free of debris. Therefore they go around ingesting numerous melanocytes and other cellular debris from epithelial cell death.

33
Q

What is the front surface of the iris called?

A

The anterior border layer.

34
Q

What is unusual about the anterior border layer of the iris?

A

It is not covered by an epithelium.

35
Q

What is the anterior border layer of the iris made up of and where is it located?

A

The location is in the diagram for reference.

It is made up of a dense layer of fibroblasts underneath which is a dense layer of melanocytes.

36
Q

What are melanocytes?

A

Melanin producing cells

37
Q

What is responsible for eye colour?

A

Mainly (other things contribute too but this is the main reason) Melanocytes - in blue-eyed people, melanocyte layer of the anterior border layer of the iris is very thin, in brown-eyed people it is thick.

38
Q

As the iris muscles are smooth what are they controlled by?

A

Autonomic Nervous system.

39
Q

Postganglionic sympathetic fibres to the eye, including those going to the iris dilatator muscle-originate from the where?

A

Postganglionic sympathetic fibres to the eye, including those going to the iris dilatator muscle, originate from the superior cervical ganglion

40
Q
A