Analgetika Generelt Flashcards

1
Q

Hvilke nerver føler smerte og hvilken smerte og myelinideringsgrad og langsom/hurtig? 2

A

A delta: akut smerte. Myeliniseret. Hurtige

C det omvendte

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2
Q

Hvilke forskellige neurotransmittere er der i dorsalhornet? 8 plus 4 underenheder

A
  1. EAA: excitatoriske Aminoglycosider acids
  2. Glutamat og aspartat AMPA og NMDA
  3. Små peptider(substans p, calcitonin, genrelateret peptid, neurokinin A
  4. Enkephalin
  5. NA
  6. Serotonin
  7. NO
  8. Prostaglandiner
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3
Q

Hvilke forskellige processer er der i nociception? 4

A

Transduktion
Transmission
Modulation
Perception

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4
Q

Hvilke analgetika virker i nerveender(nociceptorer)? 3

A

Opioider
Lokalanæstetika
Nsaids

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5
Q

Hvilke analgetika virker i transmissionen? 2 og hvordan?

A

Inhiberer impulskonduktion
Alfa2
Lokal anæstetika

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6
Q

Hvilke analgetika virker i modulation pg hvordan?

A
6
Lokal anæstetika
Alfa2
NMDA
Tricykliske
Cholinesterasehæmmere(hmm)
Nsaids
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7
Q

Hvilke analgetika virker i perception? 4

A

Benzodiazepiner
Alfa2
Anæstetika
Opioider

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8
Q

Hvordan manifesterer operstionsstress sig? 5

A
Øget cortisol, NA og adrenalin
Karambolage
Nedst sårheling
Nedsat immunrespons
Bedst cardiovaskulær reaktion
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9
Q

Hvorfor bruges der præemptiv smertebehandling ved anæstesi?

A

Ingen nociception til CNS =

Mindre brug af anæstetika, bedøvelsesstress, operstionsstress, postoperationsstress

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10
Q

Hvilke receptor er især aktiv i visceral smerte???

A

Opiod kappa

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11
Q

Hvilke analgetisk klasser er der?

5

A
Lokalanæstetika
Opioider
Nsaids
Alfa2agonister
NMDA antagonister
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